Perforin--a primary or auxiliary lytic mechanism?
Perforin--a primary or auxiliary lytic mechanism?
复制标题
穿孔素——主要或辅助裂解机制?
DOI:
10.1016/0167-5699(88)91277-7
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发表时间:
1988
期刊:
影响因子:
--
通讯作者:
W. Clark
中科院分区:
文献类型:
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作者:
W. Clark
Cytotoxic granules containing pore-forming toxins have been postulated to be the principal mechanism underlying cellmediated cytotoxicity. On the basis of recent evidence, however, William Clark suggests here that this may be a highly specialized mechanism operating only under conditions of unusual immunological stress. While this mechanism may be extremely important for host survival, it probably does not explain how cytotoxic cells normally kill their targets.
影响因子:
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作者:
Podack,ER;Konigsberg,PJ;Acha-Orbea,H;Pircher,H;Hengartner,H
通讯作者:
Hengartner,H