A data-driven framework for mapping domains of human neurobiology.
A data-driven framework for mapping domains of human neurobiology.
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用于映射人类神经生物学领域的数据驱动框架。
DOI:
10.1038/s41593-021-00948-9
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发表时间:
2021-12
影响因子:
25
通讯作者:
Etkin A
中科院分区:
文献类型:
--
作者:
Beam E;Potts C;Poldrack RA;Etkin A
Functional neuroimaging has been a mainstay of human neuroscience for the past 25 years. Interpretation of fMRI data has often occurred within knowledge frameworks crafted by experts, which have the potential to amplify biases that limit the replicability of findings. Here, we employ a computational approach to derive a data-driven framework for neurobiological domains that synthesizes the texts and data of nearly 20,000 human neuroimaging articles. Across multiple levels of domain specificity, the structure-function links within domains better replicate in held-out articles than those mapped from dominant frameworks in neuroscience and psychiatry. We further show that the data-driven framework partitions the literature into modular subfields, for which domains serve as generalizable prototypes of structure-function patterns in single articles. The approach to computational ontology we present here is the most comprehensive characterization of human brain circuits quantifiable with fMRI and may be extended to synthesize other scientific literatures.
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Janak PH;Tye KM
通讯作者:
Tye KM
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4.2
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Barrett LF
通讯作者:
Barrett LF
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82.9
作者:
Drysdale AT;Grosenick L;Downar J;Dunlop K;Mansouri F;Meng Y;Fetcho RN;Zebley B;Oathes DJ;Etkin A;Schatzberg AF;Sudheimer K;Keller J;Mayberg HS;Gunning FM;Alexopoulos GS;Fox MD;Pascual-Leone A;Voss HU;Casey BJ;Dubin MJ;Liston C
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Liston C
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McCoy TH Jr;Castro VM;Hart KL;Pellegrini AM;Yu S;Cai T;Perlis RH
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Perlis RH
影响因子:
16.6
作者:
Eisenberg, Ian W.;Bissett, Patrick G.;Poldrack, Russell A.
通讯作者:
Poldrack, Russell A.