Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report.

Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report.
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DOI:
10.3389/fsurg.2022.1068215
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发表时间:
2022
影响因子:
1.8
通讯作者:
Zhao, Gang
Zhao, Gang
中科院分区:
医学4区
文献类型:
--
作者:
Ji, Linhua;Xu, Danhua;Zhu, Chunchao;Xu, Jia;Cao, Hui;Zhao, Gang

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肝移植是十二指肠癌前病变和恶变的危险因素。肝移植后新发十二指肠恶性肿瘤的报道很少。本研究报道了一名无症状的 67 岁男性患者,十多年前接受了肝移植,随后患上十二指肠恶性肿瘤。对新发十二指肠恶性肿瘤的内镜活检表明十二指肠癌,并进行了胰十二指肠切除术 (PD)。手术后12天,患者顺利出院。胰十二指肠切除术后 14 个月,右第七肋骨发生转移性病变。术后病理检查提示肝细胞癌转移。据我们所知,此前尚未报道过此类病例。本研究揭示了一种新型十二指肠恶性肿瘤的发展、治疗、预后和管理。
Liver transplantation is a risk factor for premalignant and malignant changes of the duodenum. De novo duodenal malignancy is seldom reported after liver transplantation. The present study reports a case of an asymptomatic 67-year-old male patient who underwent liver transplantation more than 10 years ago and subsequently developed duodenal malignancy. Endoscopic biopsy of the de novo duodenal malignancy indicated duodenal carcinoma and pancreatoduodenectomy (PD) was performed. The patient was successfully discharged 12 days after the surgery. A metastatic lesion occurred at the right seventh rib 14 months after the pancreatoduodenectomy. Postoperative pathological examination indicated hepatocellular carcinoma metastasis. To the best of our knowledge, this case type has not been previously reported. The present study sheds light on the development, the treatment, the prognosis, and the management of a new type of de novo duodenal malignancy.
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发表时间: 2001-01-01
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