GeSeq - versatile and accurate annotation of organelle genomes.
GeSeq - versatile and accurate annotation of organelle genomes.
复制标题
GESEQ-细胞器基因组的多功能和准确注释。
DOI:
10.1093/nar/gkx391
复制
发表时间:
2017-07-03
影响因子:
14.9
通讯作者:
Greiner S
中科院分区:
文献类型:
--
作者:
Tillich M;Lehwark P;Pellizzer T;Ulbricht-Jones ES;Fischer A;Bock R;Greiner S
We have developed the web application GeSeq (https://chlorobox.mpimp-golm.mpg.de/geseq.html) for the rapid and accurate annotation of organellar genome sequences, in particular chloroplast genomes. In contrast to existing tools, GeSeq combines batch processing with a fully customizable reference sequence selection of organellar genome records from NCBI and/or references uploaded by the user. For the annotation of chloroplast genomes, the application additionally provides an integrated database of manually curated reference sequences. GeSeq identifies genes or other feature-encoding regions by BLAT-based homology searches and additionally, by profile HMM searches for protein and rRNA coding genes and two de novo predictors for tRNA genes. These unique features enable the user to conveniently compare the annotations of different state-of-the-art methods, thus supporting high-quality annotations. The main output of GeSeq is a GenBank file that usually requires only little curation and is instantly visualized by OGDRAW. GeSeq also offers a variety of optional additional outputs that facilitate downstream analyzes, for example comparative genomic or phylogenetic studies.
登录
查看更多内容
影响因子:
14.9
作者:
Abascal F;Zardoya R;Telford MJ
通讯作者:
Telford MJ
影响因子:
2.5
作者:
Lohse, Marc;Drechsel, Oliver;Bock, Ralph
通讯作者:
Bock, Ralph
影响因子:
5.8
作者:
Wyman, SK;Jansen, RK;Boore, JL
通讯作者:
Boore, JL
影响因子:
10.7
作者:
Alverson, Andrew J.;Wei, XiaoXin;Palmer, Jeffrey D.
通讯作者:
Palmer, Jeffrey D.
影响因子:
5.8
作者:
McKain, Michael R.;Hartsock, Ryan H.;Kellogg, Elizabeth A.
通讯作者:
Kellogg, Elizabeth A.