Aqueous/vitreous tonicity in "sugar' cataracts.
Aqueous/vitreous tonicity in "sugar' cataracts.
复制标题
“糖”白内障中的房水/玻璃体张力。
DOI:
10.1159/000266872
复制
发表时间:
1989
影响因子:
2.1
通讯作者:
Cheng,HM
中科院分区:
文献类型:
--
作者:
Xiong,H;Cheng,HM
We examined the aqueous/vitreous tonicity in ‘sugar’ cataracts. Four sets of eyes and their controls were examined: diabetic human eyes, eyes from rabbits and rats fed 50% galactose for up to 1 week, and eyes from streptozotocin-diabetic rats of up to 21 days after diabetes induction. The results showed no statistically significant increase of aqueous/vitreous tonicity in the diabetic human eye and eyes from galactose-fed rats and rabbits. Diabetic rats, on the other hand, showed large tonicity increase in the vitreous, although treatment of the diabetic rats with an aldose reductase inhibitor or insulin completely normalized the tonicity. Seven days after feeding, the galactose-fed animals already showed lens opacities, while diabetic rat lenses remained clear even after 21 days after diabetes induction. These results indicate insignificant osmotic changes in the human eye. In the rat eye, the increase of lens tonicity can be offset by a concomitant increase in the vitreous tonicity. However, this phenomenon is not observed in the galactose eyes. The nature of the osmolytes in the diabetic eye is unclear, although both glucose and sorbitol have been ruled out. The presence of an osmotic regulatory mechanism in the eye is implied.
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DOI:
--
发表时间:
1943
期刊:
影响因子:
--
作者:
S. Washburn
通讯作者:
S. Washburn
DOI:
--
发表时间:
1978
期刊:
影响因子:
--
作者:
C. Duggleby
通讯作者:
C. Duggleby
DOI:
--
发表时间:
1985
期刊:
Human Biology: The Official Publication of the American Association of Anthropological Genetics
影响因子:
--
作者:
A. Hausman;E. Wilmsen
通讯作者:
E. Wilmsen
DOI:
--
发表时间:
1979
期刊:
影响因子:
--
作者:
J. Himes
通讯作者:
J. Himes
影响因子:
9.2
作者:
C. R. Carpenter
通讯作者:
C. R. Carpenter