Aqueous/vitreous tonicity in "sugar' cataracts.

Aqueous/vitreous tonicity in "sugar' cataracts.
复制标题

“糖”白内障中的房水/玻璃体张力。

DOI:
10.1159/000266872
复制
发表时间:
1989
影响因子:
2.1
通讯作者:
Cheng,HM
Cheng,HM
中科院分区:
医学3区
文献类型:
--
作者:
Xiong,H;Cheng,HM

文献摘要

参考文献

被引文献

相似文献

我们研究了“糖”性白内障的水/玻璃体张力。对四组眼睛及其对照进行了检查:糖尿病人眼、喂食50%半乳糖长达1周的兔和大鼠眼睛以及糖尿病诱导后长达21天的链脲佐菌素糖尿病大鼠眼睛。结果显示,糖尿病人眼和半乳糖喂养大鼠和兔眼睛的房水/玻璃体张力无统计学显著增加。另一方面,糖尿病大鼠显示玻璃体中的大的张力增加,尽管用醛糖还原酶抑制剂或胰岛素治疗糖尿病大鼠使张力完全正常化。喂养7天后,半乳糖喂养的动物已经显示出透镜混浊,而糖尿病大鼠晶状体即使在糖尿病诱导后21天仍保持清晰。这些结果表明人眼中的渗透压变化不显著。在大鼠眼中,透镜张力的增加可以被玻璃体张力的伴随增加所抵消。然而,这种现象在半乳糖眼中没有观察到。虽然葡萄糖和山梨糖醇都已被排除,但糖尿病患者眼睛中渗透压物质的性质尚不清楚。这意味着眼睛中存在渗透调节机制。
We examined the aqueous/vitreous tonicity in ‘sugar’ cataracts. Four sets of eyes and their controls were examined: diabetic human eyes, eyes from rabbits and rats fed 50% galactose for up to 1 week, and eyes from streptozotocin-diabetic rats of up to 21 days after diabetes induction. The results showed no statistically significant increase of aqueous/vitreous tonicity in the diabetic human eye and eyes from galactose-fed rats and rabbits. Diabetic rats, on the other hand, showed large tonicity increase in the vitreous, although treatment of the diabetic rats with an aldose reductase inhibitor or insulin completely normalized the tonicity. Seven days after feeding, the galactose-fed animals already showed lens opacities, while diabetic rat lenses remained clear even after 21 days after diabetes induction. These results indicate insignificant osmotic changes in the human eye. In the rat eye, the increase of lens tonicity can be offset by a concomitant increase in the vitreous tonicity. However, this phenomenon is not observed in the galactose eyes. The nature of the osmolytes in the diabetic eye is unclear, although both glucose and sorbitol have been ruled out. The presence of an osmotic regulatory mechanism in the eye is implied.
DOI: --
发表时间: 1943
期刊:
影响因子: --
作者:
S. Washburn
通讯作者: S. Washburn
DOI: --
发表时间: 1978
期刊:
影响因子: --
作者:
C. Duggleby
通讯作者: C. Duggleby
经济变化和桑族儿童成长的长期趋势。
DOI: --
发表时间: 1985
期刊: Human Biology: The Official Publication of the American Association of Anthropological Genetics
影响因子: --
作者:
A. Hausman;E. Wilmsen
通讯作者: E. Wilmsen
身体比例和成分的长期变化
DOI: --
发表时间: 1979
期刊:
影响因子: --
作者:
J. Himes
通讯作者: J. Himes
波多黎各圣地亚哥岛上的猕猴和长臂猿繁殖地
DOI: 10.1159/000393401
发表时间: 1971
期刊: Current Biology
影响因子: 9.2
作者:
C. R. Carpenter
通讯作者: C. R. Carpenter