A comprehensive overview of radioguided surgery using gamma detection probe technology.

A comprehensive overview of radioguided surgery using gamma detection probe technology.
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DOI:
10.1186/1477-7819-7-11
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发表时间:
2009-01-27
影响因子:
3.2
通讯作者:
Martin EW Jr
Martin EW Jr
中科院分区:
医学3区
文献类型:
--
作者:
Povoski SP;Neff RL;Mojzisik CM;O'Malley DM;Hinkle GH;Hall NC;Murrey DA Jr;Knopp MV;Martin EW Jr

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The concept of radioguided surgery, which was first developed some 60 years ago, involves the use of a radiation detection probe system for the intraoperative detection of radionuclides. The use of gamma detection probe technology in radioguided surgery has tremendously expanded and has evolved into what is now considered an established discipline within the practice of surgery, revolutionizing the surgical management of many malignancies, including breast cancer, melanoma, and colorectal cancer, as well as the surgical management of parathyroid disease. The impact of radioguided surgery on the surgical management of cancer patients includes providing vital and real-time information to the surgeon regarding the location and extent of disease, as well as regarding the assessment of surgical resection margins. Additionally, it has allowed the surgeon to minimize the surgical invasiveness of many diagnostic and therapeutic procedures, while still maintaining maximum benefit to the cancer patient. In the current review, we have attempted to comprehensively evaluate the history, technical aspects, and clinical applications of radioguided surgery using gamma detection probe technology.
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