Glucose as the Fifth Vital Sign: A Randomized Controlled Trial of Continuous Glucose Monitoring in a Non-ICU Hospital Setting.
Glucose as the Fifth Vital Sign: A Randomized Controlled Trial of Continuous Glucose Monitoring in a Non-ICU Hospital Setting.
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DOI：
10.2337/dc20-1016
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发表时间：
2020-11
期刊：
影响因子：
16.2
通讯作者：
Philis-Tsimikas A
中科院分区：
文献类型：
--
作者：
Fortmann AL;Spierling Bagsic SR;Talavera L;Garcia IM;Sandoval H;Hottinger A;Philis-Tsimikas A
目前医院血糖管理的标准是即时检测（POC）。我们进行了一项随机对照试验，将实时连续血糖监测（RT-CGM）与非重症监护病房（ICU）的POC进行比较。共有110名非icu楼层的成人2型糖尿病患者接受了Dexcom G6与常规护理（UC）的RT-CGM。RT-CGM数据从床边无线传输。医院遥测监测RT-CGM数据，并通知床边护理血糖警报和趋势。采用标准化方案进行干预。与UC相比，RT-CGM组平均血糖（M∆= - 18.5 mg/dL）和高血糖状态（bb0 ~ 250 mg/dL）的时间百分比（- 11.41%）显著降低，70 ~ 250 mg/dL的时间百分比（+11.26%）显著提高（P值<0.05）。低血糖的时间百分比非常低。RT-CGM可成功用于社区医院非icu环境，以改善血糖管理。连续不断的血糖读数可能真的是第五个生命体征。
The current standard for hospital glucose management is point-of-care (POC) testing. We conducted a randomized controlled trial of real-time continuous glucose monitoring (RT-CGM) compared with POC in a non–intensive care unit (ICU) hospital setting. A total of 110 adults with type 2 diabetes on a non-ICU floor received RT-CGM with Dexcom G6 versus usual care (UC). RT-CGM data were wirelessly transmitted from the bedside. Hospital telemetry monitored RT-CGM data and notified bedside nursing of glucose alerts and trends. Standardized protocols were used for interventions. The RT-CGM group demonstrated significantly lower mean glucose (M∆ = −18.5 mg/dL) and percentage of time in hyperglycemia >250 mg/dL (−11.41%) and higher time in range 70–250 mg/dL (+11.26%) compared with UC (P values <0.05). Percentage of time in hypoglycemia was very low. RT-CGM can be used successfully in community-based hospital non-ICU settings to improve glucose management. Continuously streaming glucose readings may truly be the fifth vital sign.
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