Smoking-related general and cause-specific mortality in Estonia.
Smoking-related general and cause-specific mortality in Estonia.
复制标题
爱沙尼亚吸烟有关的一般和特定原因死亡率。
DOI：
10.1186/s12889-017-4590-3
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发表时间：
2017-07-19
影响因子：
4.5
通讯作者：
Kõks S
中科院分区：
文献类型：
--
作者：
Kõks G;Fischer K;Kõks S
众所周知，吸烟是全球过早死亡的最大单一原因。本研究的目的是分析吸烟对爱沙尼亚人口的一般死亡率和死因死亡率的影响。研究使用了来自塔尔图大学爱沙尼亚基因组中心的51,756名成年人的数据。从国家死亡原因登记处检索有关死亡日期和原因的信息。使用Kaplan-Meier估计和考克斯比例风险模型分析吸烟状况、总体生存率、总体死亡率和死因特异性死亡率。研究发现，吸烟使男性的中位生存期缩短了11.4年，女性缩短了5.8年。吸烟在死亡原因方面产生了一种非常特殊的模式，大大增加了各种癌症和心血管疾病的风险，这些疾病是男性和女性的死亡原因。这项研究还发现，外部原因，如酒精中毒和故意自残，是吸烟者比非吸烟者更普遍的死亡原因。此外，戒烟被发现可以扭转过早死亡的风险增加。吸烟仍然是导致癌症和心血管疾病的主要原因。除了常见疾病外，外部原因也会大大缩短寿命。死亡的外部原因表明，吸烟对吸烟者的行为有长期影响，引起自我毁灭行为。我们的研究支持这样的观点，即吸烟对我们的健康产生复杂的危害，增加了躯体和精神疾病的死亡率。
Tobacco smoking is known to be the single largest cause of premature death worldwide. The aim of present study was to analyse the effect of smoking on general and cause-specific mortality in the Estonian population. The data from 51,756 adults in the Estonian Genome Center of the University of Tartu was used. Information on dates and causes of death was retrieved from the National Causes of Death Registry. Smoking status, general survival, general mortality and cause-specific mortality were analysed using Kaplan-Meier estimator and Cox proportional hazards models. The study found that smoking reduces median survival in men by 11.4 years and in women by 5.8 years. Tobacco smoking produces a very specific pattern in the cause of deaths, significantly increasing the risks for different cancers and cardiovascular diseases as causes of death for men and women. This study also identified that external causes, such as alcohol intoxication and intentional self-harm, are more prevalent causes of death among smokers than non-smokers. Additionally, smoking cessation was found to reverse the increased risks for premature mortality. Tobacco smoking remains the major cause for losses of life inducing cancers and cardiovascular diseases. In addition to the common diseases, external causes also reduce substantially the years of life. External causes of death indicate that smoking has a long-term influence on the behaviour of smokers, provoking self-destructive behaviour. Our study supports the idea, that tobacco smoking generates complex harm to our health increasing mortality from both somatic and mental disorders.
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影响因子：
168.9
作者：
Pirie, Kirstin;Peto, Richard;Beral, Valerie
通讯作者：
Beral, Valerie
影响因子：
2.9
作者：
Pizzo de Castro, Marcia Regina;Maes, Michael;Vargas Nunes, Sandra Odebrecht
通讯作者：
Vargas Nunes, Sandra Odebrecht
影响因子：
5.2
作者：
Jamrozik, Konrad;McLaughlin, Deirdre;Dobson, Annette
通讯作者：
Dobson, Annette
在一项43年随访的队列研究中，终生吸烟史和特定原因死亡率。
影响因子：
3.7
作者：
Taghizadeh N;Vonk JM;Boezen HM
通讯作者：
Boezen HM
影响因子：
5.2
作者：
Kenfield, Stacey A.;Wei, Esther K.;Colditz, Graham A.
通讯作者：
Colditz, Graham A.