FDG-PET in differentiating lymphoma from nonmalignant central nervous system lesions in patients with AIDS.
FDG-PET in differentiating lymphoma from nonmalignant central nervous system lesions in patients with AIDS.
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FDG-PET 区分艾滋病患者淋巴瘤和非恶性中枢神经系统病变。
DOI：
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发表时间：
1993
影响因子：
9.3
通讯作者：
R. Coleman
中科院分区：
文献类型：
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作者：
J. Hoffman;H. Waskin;T. Schifter;M. Hanson;Linda Gray;S. Rosenfeld;R. Coleman
结构成像研究，如CT或MRI不能准确区分感染性和恶性脑病变的艾滋病患者。我们研究了11例艾滋病和中枢神经系统（CNS）病变与18氟-2-脱氧葡萄糖（FDG）和正电子发射断层扫描（PET）。FDG-PET能够准确区分CNS病变的恶性（淋巴瘤）和非恶性病因。进行了图像的定性目视检查以及使用计数比的半定量分析，结果相似。FDG-PET可能是有用的，在管理艾滋病患者的中枢神经系统病变，因为高FDG摄取最有可能代表一个恶性的过程，应活检确认，而不是治疗假定为传染性。
Structural imaging studies such as CT or MRI are not able to accurately differentiate infectious from malignant cerebral lesions in patients with AIDS. We studied 11 individuals with AIDS and central nervous system (CNS) lesions with 18F-fluoro-2-deoxyglucose (FDG) and positron emission tomography (PET). FDG-PET was able to accurately differentiate between a malignant (lymphoma) and nonmalignant etiology for the CNS lesions. Both qualitative visual inspection of the images as well as semiquantitative analysis using count ratios was performed and revealed similar results. FDG-PET may be useful in the management of AIDS patients with CNS lesions since high FDG uptake most likely represents a malignant process which should be biopsied for confirmation rather than treated presumptively as infectious.
影响因子：
1.1
作者：
Karl H. Anders;K. Steinsapir;Iverson Dj;B. J. Glasgow;L. Layfield;Brown Wj;P. Cancilla;M. Verity;H. V. Vinters
通讯作者：
Karl H. Anders;K. Steinsapir;Iverson Dj;B. J. Glasgow;L. Layfield;Brown Wj;P. Cancilla;M. Verity;H. V. Vinters