cMIND Diet, Indoor Air Pollution, and Depression: A Cohort Study Based on the CLHLS from 2011 to 2018.
cMIND Diet, Indoor Air Pollution, and Depression: A Cohort Study Based on the CLHLS from 2011 to 2018.
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DOI：
10.3390/nu15051203
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发表时间：
2023-02-27
期刊：
影响因子：
5.9
通讯作者：
Zhang Z
中科院分区：
文献类型：
--
作者：
Wang R;Ye C;Huang X;Halimulati M;Sun M;Ma Y;Fan R;Zhang Z
本研究旨在探讨中国版的地中海-DASH神经退行性延迟（cMIND）饮食干预与室内空气污染之间的相互作用及其对老年人抑郁症的影响。这项队列研究使用了2011-2018年中国健康长寿纵向调查的数据。参与者包括2724名65岁及以上的成年人，没有抑郁症。基于经验证的食物频率问卷回答，Mediterranean-DASH干预神经退行性延迟（cMIND）饮食评分的中文版本范围为0 - 12。抑郁症是使用表型和EXposures工具包测量的。使用考克斯比例风险回归模型来探索相关性，并使用cMIND饮食评分对分析进行分层。基线时共纳入2724例受试者（54.3%为男性，45.9%为80岁及以上）。与没有室内污染的生活相比，生活在严重的室内污染中与抑郁症风险增加40%相关（HR：1.40，95%CI：1.07，1.82）。室内空气污染暴露与cMIND饮食评分显著相关。cMIND饮食评分较低的参与者（HR：1.72，95% CI：1.24，2.38）与严重污染的关联大于cMIND饮食评分较高的参与者。cMIND饮食可以减轻老年人室内污染引起的抑郁症。
This study aims to explore the interaction between a Chinese version of the Mediterranean–DASH intervention for neurodegenerative delay (cMIND) diet and indoor air pollution and its effect on depression among older adults. This cohort study used 2011–2018 data from the Chinese Longitudinal Healthy Longevity Survey. Participants included 2724 adults aged 65 and older without depression. The Chinese version of the Mediterranean–DASH intervention for neurodegenerative delay (cMIND) diet scores ranged from 0 to 12 based on validated food frequency questionnaire responses. Depression was measured using the Phenotypes and eXposures Toolkit. Cox proportional hazards regression models were used to explore the associations, and the analysis was stratified using the cMIND diet scores. A total of 2724 participants (54.3% males and 45.9% 80 years and older) at baseline were included. Living with severe indoor pollution was associated with a 40% increase in the risk of depression (HR: 1.40, 95% CI: 1.07, 1.82) compared to living without indoor pollution. Indoor air pollution exposure was significantly associated with cMIND diet scores. Participants with a lower cMIND diet score (HR: 1.72, 95% CI: 1.24, 2.38) had a greater association with severe pollution than those with a higher cMIND diet score. The cMIND diet may alleviate depression caused by indoor pollution among older adults.
影响因子：
1.2
作者：
Torres, German;Mourad, Mervat;Leheste, Joerg R.
通讯作者：
Leheste, Joerg R.