Indoor Air Pollution and Decision-Making Behavior: An Interdisciplinary Review.
Indoor Air Pollution and Decision-Making Behavior: An Interdisciplinary Review.
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DOI：
10.7759/cureus.26247
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发表时间：
2022-06
影响因子：
1.2
通讯作者：
Leheste, Joerg R.
中科院分区：
文献类型：
--
作者：
Torres, German;Mourad, Mervat;Leheste, Joerg R.
关键词：
人类大脑经常暴露在空气污染物中，其中一些污染物可能会对与认知功能抽象特征有关的某些神经元造成破坏，甚至致命。在这篇综述中，我们提出了人类行为和神经研究的新证据，表明室内细颗粒物与决策行为之间存在联系。为了说明这种关系，我们使用定性来源（例如越南战争的历史文献）来提出假设，以了解污染物的空中传播如何在政策决策评估期间阻碍替代选择。我们首先通过解决神经元及其同源受体如何直接评估物理现象并将其转换为感官知觉来描述驱动决策过程的神经回路，从而使我们能够在竞争性替代方案中决定最佳行动方案。然后，我们提出室内空气污染物也可能影响脑实质外的细胞信号系统的可能性，从而进一步阻碍对社会环境的计算分析。我们还强调了颗粒物如何病理性地整合到大脑中，从而超越对感官决策的控制，从而扰乱选择的选择。这些研究旨在加深我们对吸入空气中的颗粒物和烟雾中的有毒物质如何导致认知障碍和负面健康结果的理解。
The human brain is constantly exposed to air pollutants, some of which might be disruptive or even lethal to certain neurons implicated in abstract features of cognitive function. In this review, we present new evidence from behavioral and neural studies in humans, suggesting a link between indoor fine particulate matter and decision-making behavior. To illustrate this relationship, we use qualitative sources, such as historical documents of the Vietnam War to develop hypotheses of how aerial transmission of pollutants might obstruct alternative choices during the evaluation of policy decisions. We first describe the neural circuits driving decision-making processes by addressing how neurons and their cognate receptors directly evaluate and transduce physical phenomena into sensory perceptions that allow us to decide the best course of action among competing alternatives. We then raise the possibility that indoor air pollutants might also impact cell-signaling systems outside the brain parenchyma to further obstruct the computational analysis of the social environment. We also highlight how particulate matter might be pathologically integrated into the brain to override control of sensory decisions, and thereby perturb selection of choice. These lines of research aim to extend our understanding of how inhalation of airborne particulates and toxicants in smoke, for example, might contribute to cognitive impairment and negative health outcomes.
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DOI：
10.1523/jneurosci.0392-21.2021
发表时间：
2021-10-06
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Kaanders P;Nili H;O'Reilly JX;Hunt L
通讯作者：
Hunt L
DOI：
10.1073/pnas.1820838116
发表时间：
2020-09-22
影响因子：
11.1
作者：
Aristizabal, Maria J.;Anreiter, Ina;O'Donnell, Kieran J.
通讯作者：
O'Donnell, Kieran J.
影响因子：
1.6
作者：
Calderon-Garciduenas, Lilian;Calderon-Garciduenas, Ana;Angiulli, Amedeo D.
通讯作者：
Angiulli, Amedeo D.
影响因子：
4.1
作者：
Cui, Xiaoying;Gooch, Helen;Eyles, Darryl
通讯作者：
Eyles, Darryl
DOI：
10.1073/pnas.2018995118
发表时间：
2021-04-27
影响因子：
11.1
作者：
Bazant MZ;Bush JWM
通讯作者：
Bush JWM