Chromosomal assignment of the human homologue encoding SGP-2.

Chromosomal assignment of the human homologue encoding SGP-2.
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编码 SGP-2 的人类同源物的染色体分配。

DOI:
10.1016/s0006-291x(05)80187-1
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发表时间:
1990
影响因子:
3.1
通讯作者:
Buttyan,R
Buttyan,R
中科院分区:
生物学4区
文献类型:
--
作者:
Slawin,K;Sawczuk,IS;Olsson,CA;Buttyan,R

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硫酸化糖蛋白-2(sulfated glycoprotein-2,SGP-2)最初是哺乳动物支持细胞中的一种组成型表达基因产物,但由于其在多种哺乳动物细胞中的快速诱导作用而引起广泛关注。为了鉴定SGP-2的人同源物的染色体分配,我们对从一组克隆的仓鼠-人杂交细胞系中提取的Bgl II限制性基因组DNA进行Southern印迹分析,并筛选与SGP-2同源的限制性片段的存在。该分析的结果表明,SGP-2的人类同源物位于8号染色体上。
Although originally characterized as a constituitively expressed gene product in mammalian Sertoli cells, sulfated glycoprotein-2 (SGP-2) has gained widespread attention due to its remarkably rapid and sizable induction in numerous types of mammalian cells undergoing apoptosis, or programmed death. In order to identify the chromosomal assignment for the human homologue of SGP-2, we performed Southern blot analysis of Bgl II restricted genomic DNA extracted from a panel of cloned hamster-human hybrid cell lines and screened for the presence of restriction fragments homologous to SGP-2. The results of this analysis indicate that the human homologue of SGP-2 resides on chromosome 8.
雄激素程序性细胞死亡过程中表达的基因产物的表征及其作为泌尿生殖损伤标志物的潜在用途。
DOI: 10.1016/s0022-5347(17)39975-5
发表时间: 1990
期刊: The Journal of urology
影响因子: --
作者:
Bandyk,MG;Sawczuk,IS;Olsson,CA;Katz,AE;Buttyan,R
通讯作者: Buttyan,R
DOI: 10.1016/s0006-291x(88)81099-4
发表时间: 1988-08
影响因子: 3.1
作者:
C. Cheng;C. L. Chen;Z. Feng;A. Marshall;C. Bardin
通讯作者: C. Cheng;C. L. Chen;Z. Feng;A. Marshall;C. Bardin
DOI: 10.1089/dna.1983.2.329
发表时间: 1983-01-01
期刊: DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY
影响因子: --
作者:
CATHALA, G;SAVOURET, JF;BAXTER, JD
通讯作者: BAXTER, JD
DOI: 10.1021/bi00386a008
发表时间: 1987-06-16
期刊: BIOCHEMISTRY
影响因子: 2.9
作者:
COLLARD, MW;GRISWOLD, MD
通讯作者: GRISWOLD, MD