Ethyl carbamate in alcoholic beverages from Mexico (tequila, mezcal, bacanora, sotol) and Guatemala (cuxa): market survey and risk assessment.

Ethyl carbamate in alcoholic beverages from Mexico (tequila, mezcal, bacanora, sotol) and Guatemala (cuxa): market survey and risk assessment.
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DOI:
10.3390/ijerph6010349
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发表时间:
2009-01
影响因子:
--
通讯作者:
Rehm J
Rehm J
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Lachenmeier DW;Kanteres F;Kuballa T;López MG;Rehm J

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氨基甲酸乙酯(EC)是一种公认​​的遗传毒性致癌物,广泛存在于发酵食品和饮料中。没有关于墨西哥或中美洲酒精饮料中存在该物质的数据。龙舌兰酒样品包括龙舌兰酒、梅斯卡尔酒、巴卡诺拉酒和索托尔酒 (n=110),以及甘蔗酒酒 cuxa (n=16) 的样品分别在墨西哥和危地马拉购买,并进行了 EC 分析。墨西哥的 EC 污染发生率高于危地马拉,但浓度低于国际指导水平(<0.15 mg/L)。风险评估发现暴露幅度 (MOE) 与欧洲烈酒的暴露幅度一致。因此,EC 不太可能在墨西哥报道的高肝硬化发病率中发挥作用。
Ethyl carbamate (EC) is a recognized genotoxic carcinogen, with widespread occurrence in fermented foods and beverages. No data on its occurrence in alcoholic beverages from Mexico or Central America is available. Samples of agave spirits including tequila, mezcal, bacanora and sotol (n=110), and of the sugarcane spirit cuxa (n=16) were purchased in Mexico and Guatemala, respectively, and analyzed for EC. The incidence of EC contamination was higher in Mexico than in Guatemala, however, concentrations were below international guideline levels (<0.15 mg/L). Risk assessment found the Margin of Exposure (MOE) in line with that of European spirits. It is therefore unlikely that EC plays a role in high rates of liver cirrhosis reported in Mexico.
DOI: 10.1111/j.1360-0443.2009.02507.x
发表时间: 2009-05-01
期刊: ADDICTION
影响因子: 6
作者:
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DOI: 10.1016/j.foodchem.2007.01.048
发表时间: 2007-01-01
期刊: FOOD CHEMISTRY
影响因子: 8.8
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影响因子: 6.1
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期刊: ZEITSCHRIFT FUR LEBENSMITTEL-UNTERSUCHUNG UND-FORSCHUNG
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