Determinants of intermittent preventive treatment of malaria during pregnancy (IPTp) utilization in a rural town in Western Nigeria.

Determinants of intermittent preventive treatment of malaria during pregnancy (IPTp) utilization in a rural town in Western Nigeria.
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DOI:
10.1186/1742-4755-9-12
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发表时间:
2012-08-13
影响因子:
3.4
通讯作者:
Iyaniwura CA
Iyaniwura CA
中科院分区:
医学2区
文献类型:
--
作者:
Amoran OE;Ariba AA;Iyaniwura CA

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妊娠期疟疾感染是孕产妇和儿童死亡的主要危险因素,并大大增加流产、死产和低出生体重的风险。因此,本研究的目的是评估尼日利亚西部乡村城镇孕妇使用间歇性疟疾预防治疗 [IPTp] 的流行率和决定因素。本研究是一项分析横断面研究。所有即将分娩并在 2 个月内到尼日利亚萨加穆镇三个初级保健中心就诊的孕妇都被招募到了这项研究中。使用半结构化问卷来收集相关信息。该研究总共招募了 255 名孕妇。受访者的平均年龄为28.07±5.12岁。平均平价和预订年龄分别为 2.7±1.67 个月和 4.42±1.7 个月。过去 3 个月疟疾发病率为 122 例(47.8%)。只有 107/255 (40.4%) 的人在当前怀孕期间采取 IPTp 预防疟疾,其中只有 14.6% 的人在怀孕期间按照建议服用第二剂。氯喹 [27.1%] 是治疗妊娠期疟疾最常用的药物。提前预订年龄 [OR = 1.11,C.I = 0.61–2.01]、不良末次妊娠结局 [OR = 1.23,C.I = 0.36–4.22] 和胎次 [OR = 1.87,C.I = 0.25–16.09] 均不受影响与 IPTp 使用率有统计学显着相关性。 IPTp 使用的唯一预测因素是使用多变量分析的疟疾预防知识 [OR = 2.47,C.I = 1.06–3.52]。研究得出的结论是,大多数在尼日利亚农村地区参加 ANC 的妇女没有按预期接受 IPTp。研究人群中使用 IPTp 的一个主要决定因素是预防疟疾的知识。这项研究强调了孕妇健康教育对于提高 IPTp 吸收率的重要性,尽管资源匮乏国家农村地区的机构经常出现药物库存短缺。
Malaria infection in pregnancy is a major risk factor for maternal and child death, and substantially increases the risk of miscarriage, stillbirth and low birthweight. The aim of this study therefore is to assess the prevalence and determinants of Intermittent preventive treatment of Malaria [IPTp] utilization by pregnant women in a rural town in Western Nigeria. This study is an analytical cross-sectional study. All pregnant women that were due for delivery and were attending the three primary health care center in Sagamu town, Nigeria within a 2 months period were recruited into the study. A semi- structured questionnaire was used to collect relevant information. A total of 255 pregnant women were recruited into the study. The mean age of respondents was 28.07 ± 5.12 years. The mean parity and booking age was 2.7 ± 1.67 and 4.42 ± 1.7 months respectively. The prevalence of Malaria attack in the last 3 months was 122(47.8%). Only 107/255 (40.4%) practice IPTp for malaria prevention during the current pregnancy, with only 14.6% of them taking the second dose during pregnancy as recommended. Chloroquine [27.1%] was the most frequently used medication for the treatment of Malaria in Pregnancy. Early booking age [OR = 1.11, C.I = 0.61–2.01], adverse last pregnancy outcome [OR = 1.23, C.I = 0.36–4.22], and parity [OR = 1.87, C.I = 0.25–16.09] were not statistically significantly associated with IPTp utilization. The only predictor of IPTp use was the knowledge of prophylaxis for malaria prevention [OR = 2.47, C.I = 1.06–3.52] using multivariate analysis. The study concludes that most women who attend ANC in rural areas in Nigeria do not receive IPTp as expected. A major determinant of utilization of IPTp among the study population was the knowledge of prophylaxis for malaria prevention. This study highlights the importance of health education of the pregnant women in increasing IPTp uptake despite the regular drug stock out at the facility level in rural areas in low resource countries.
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