Role of the olivo-cerebellar complex in motor learning and control
Role of the olivo-cerebellar complex in motor learning and control
复制标题
橄榄小脑复合体在运动学习和控制中的作用
DOI：
--
复制
发表时间：
2013
期刊：
影响因子：
--
通讯作者：
M. Kawato
中科院分区：
文献类型：
--
作者：
N. Schweighofer;E. Lang;M. Kawato
尽管下橄榄（IO）输入的放电非常低，但小脑如何能够有效地进行运动学习和控制？下橄榄（IO）输入被认为携带学习所需的错误并有助于在线运动控制。IO神经元形成了成人大脑中最大的电偶联网络。在这里，我们讨论了中间耦合强度如何导致混沌共振并增加错误信号的信息传输，尽管IO发射速率非常低。与弱耦合或强耦合相比，这种增加的信息传输可以导致更有效的学习。此外，我们认为通过浦肯野细胞-小脑深部神经元- IO三角形动态调制IO电耦合可以加速学习并改善在线控制。最初，强耦合将允许大误差传递到多个功能相关的浦肯野细胞，导致快速但粗糙的学习，以及对小脑深部核和在线运动控制的显着影响。在学习的后期阶段，减少耦合将允许不同步的IO发射，允许高保真的错误传输，导致较慢但精细的学习，以及很少的在线电机控制效果。
How is the cerebellum capable of efficient motor learning and control despite very low firing of the inferior olive (IO) inputs, which are postulated to carry errors needed for learning and contribute to on-line motor control? IO neurons form the largest electrically coupled network in the adult human brain. Here, we discuss how intermediate coupling strengths can lead to chaotic resonance and increase information transmission of the error signal despite the very low IO firing rate. This increased information transmission can then lead to more efficient learning than with weak or strong coupling. In addition, we argue that a dynamic modulation of IO electrical coupling via the Purkinje cell-deep cerebellar neurons – IO triangle could speed up learning and improve on-line control. Initially strong coupling would allow transmission of large errors to multiple functionally related Purkinje cells, resulting in fast but coarse learning as well as significant effects on deep cerebellar nucleus and on-line motor control. In the late phase of learning decreased coupling would allow desynchronized IO firing, allowing high-fidelity transmission of error, resulting in slower but fine learning, and little on-line motor control effects.
影响因子：
2.5
作者：
Tseng, Ya-weng;Diedrichsen, Jorn;Bastian, Amy J.
通讯作者：
Bastian, Amy J.
均匀的橄榄小脑传导时间是大鼠小脑中浦肯野细胞复合体尖峰同步性的基础。
DOI：
10.1113/jphysiol.1993.sp019857
发表时间：
1993
期刊：
The Journal of physiology
影响因子：
--
作者：
Sugihara,I;Lang,EJ;Llinás,R
通讯作者：
Llinás,R