Painful gingivitis may be an early sign of infection with the human immunodeficiency virus.
Painful gingivitis may be an early sign of infection with the human immunodeficiency virus.
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疼痛性牙龈炎可能是人类免疫缺陷病毒感染的早期症状。
DOI:
10.1093/clind/16.2.233
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发表时间:
1993
期刊:
影响因子:
--
通讯作者:
Kaplowitz,LG
中科院分区:
文献类型:
--
作者:
Rowland,RW;Escobar,MR;Friedman,RB;Kaplowitz,LG
Anecdotal reports have suggested that painful gingivitis may be associated with infection due to the human immunodeficiency virus (HIV). Twenty patients who presented to the emergency department with a chief complaint of gum pain were evaluated for HIV infection, CD4/CD8 T lymphocyte profiles, complete blood cell counts and differentials, and lymphocyte function (response to mitogenic stimulation). Seven of the 20 patients (35%) were seropositive for HIV. Three of the seven HIV-seropositive patients were unaware of their HIV infection until tested in this study (with use of an ELISA and western blotting). The HIV-seropositive patients were significantly older than the HIV-seronegative patients (31.4 ± 3 years and 24 ± 1 year, respectively). Two of the seven HIV-seropositive patients presented with severe CD4 lymphocyte depletion. The other five HIV-seropositive patients presented with CD4 lymphocyte counts of 473 ±155 (mean ± SE). Regardless of HIV serological status, all patients demonstrated a severely depressed mitogenic response when compared with control subjects. There were no remarkable differences in complete blood cell counts and differentials within each serological group. Significant differences, however, were noted when CD4/CD8 lymphocyte counts and ratios were measured. Identification of clinical presentations, such as painful gingivitis, that reflect an early stage of HIV infection could aid in the timing of therapy and prevention of the spread of HIV infection.
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DOI:
--
发表时间:
1989
期刊:
Journal of Acquired Immune Deficiency Syndromes
影响因子:
--
作者:
J. Brinchmann;F. Vartdal;E. Thorsby
通讯作者:
E. Thorsby
DOI:
--
发表时间:
1987
期刊:
The Journal of the American Dental Association (1939)
影响因子:
--
作者:
S. Silverman
通讯作者:
S. Silverman
DOI:
--
发表时间:
1983
期刊:
Psychiatric medicine
影响因子:
--
作者:
S. Cohen;R. Cogen;A. W. Stevens;K. Kirk;E. Gaitán;J. Bird;R. Cooksey;A. Freeman
通讯作者:
A. Freeman
DOI:
--
发表时间:
1989
期刊:
Oral surgery, oral medicine, and oral pathology
影响因子:
--
作者:
J. Pindborg
通讯作者:
J. Pindborg
影响因子:
3
作者:
R. Redfield;D. Burke
通讯作者:
D. Burke