Design of NIDA CTN Protocol 0047: screening, motivational assessment, referral, and treatment in emergency departments (SMART-ED).
Design of NIDA CTN Protocol 0047: screening, motivational assessment, referral, and treatment in emergency departments (SMART-ED).
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DOI：
10.3109/00952990.2011.596971
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发表时间：
2011-09
期刊：
影响因子：
--
通讯作者：
Walker R
中科院分区：
文献类型：
--
作者：
Bogenschutz MP;Donovan DM;Adinoff B;Crandall C;Forcehimes AA;Lindblad R;Mandler RN;Oden NL;Perl HI;Walker R
医疗机构，如急诊科（EDs）提供了一个机会来识别和提供服务的个人物质使用问题，否则可能永远不会得到任何形式的评估，转诊，或干预。虽然筛选、短暂干预和转诊治疗（SBIRT）模式已被广泛研究，并被认为对在急诊科和其他医疗环境中出现酒精问题的个人有效，但这种干预措施对急诊科出现的吸毒者的有效性尚未确定。本文描述了NIDA临床试验网络协议的设计，该协议测试了SBIRT模型在医疗急诊病中的有效性，并强调了与其他针对医疗环境中物质使用行为的研究设计相关的注意事项。描述了协议，并讨论了关键的设计决策。设计挑战包括确定处理条件、研究人群和场地特征；开发筛选流程；选择主要结果；平衡评价的简洁性和全面性；并选择策略进行统计分析。本研究设计中出现的许多问题将与未来在医疗环境中干预成瘾的研究有关。最佳试验设计对于确定如何最好地将药物滥用干预措施纳入医疗保健至关重要。
Medical settings such as emergency departments (EDs) present an opportunity to identify and provide services for individuals with substance use problems who might otherwise never receive any form of assessment, referral, or intervention. Although Screening, Brief Intervention, and Referral to Treatment (SBIRT) models have been extensively studied and are considered effective for individuals with alcohol problems presenting in emergency departments and other medical settings, the efficacy of such interventions has not been established for drug users presenting in EDs. This paper describes the design of a NIDA Clinical Trials Network protocol testing the efficacy of an SBIRT model in medical EDs, highlighting considerations that that are pertinent to the design of other studies targeting substance use behaviors in medical treatment settings. The protocol is described, and critical design decisions are discussed. Design challenges included defining treatment conditions, study population, and site characteristics; developing the screening process; choosing the primary outcome; balancing brevity and comprehensiveness of assessment; and selecting the strategy for statistical analysis. Many of the issues arising in the design of this study will be relevant to future studies of interventions for addictions in medical settings. Optimal trial design is critical to determining how best to integrate substance abuse interventions into medical care.
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影响因子：
9
作者：
Gentilello, LM;Rivara, FP;Ries, RR
通讯作者：
Ries, RR
DOI：
10.1097/01.ta.0000174682.13138.a3
发表时间：
2005-09-01
影响因子：
--
作者：
Dunn, C;Ostafin, B
通讯作者：
Ostafin, B
影响因子：
3.9
作者：
Hatcher, RL;Gillaspy, JA
通讯作者：
Gillaspy, JA
影响因子：
--
作者：
Bush, K;Kivlahan, DR;Bradley, KA
通讯作者：
Bradley, KA
影响因子：
3.4
作者：
Clifford, Patrick R.;Maisto, Stephen A.;Davis, Christine M.
通讯作者：
Davis, Christine M.