Basic properties of apatite cement containing spherical tetracalcium phosphate made with plasma melting method.

Basic properties of apatite cement containing spherical tetracalcium phosphate made with plasma melting method.
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等离子熔融法制备球形磷酸四钙磷灰石骨水泥的基本性能

DOI:
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发表时间:
2004
期刊:
Journal of materials science. Materials in medicine
影响因子:
--
通讯作者:
K. Suzuki
K. Suzuki
中科院分区:
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文献类型:
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作者:
K. Ishikawa;S. Matsuya;M. Nakagawa;K. Udoh;K. Suzuki

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磷灰石水泥(AC)可通过注射器注入并形成磷灰石团块。因此,AC对于旨在重建骨缺损的微创外科手术非常有用。然而,当前AC的可注射性对于其临床应用而言并不令人满意。因此,在这项研究中,球形磷酸四钙(s-TTCP)的制备等离子体熔融法和它的效果的可注射性以及AC的其他基本性能进行了评估。当我们使用s-TTCP作为AC(s-AC)的组分时,我们发现更好的处理性质和注射性。例如,当粉液混合比为2.5时,用作s-AC浆的稠度指标的水泥铺展面积为512 mm 2,而具有不规则TTCP的普通AC(i-AC)的水泥铺展面积为158 mm 2。然而,当粉液比为4.0时,s-AC组的径向拉伸强度(1.4 MPa)显著低于i-AC组的径向拉伸强度(10.7 MPa)。X-射线粉末衍射分析表明,在s-AC的情况下,磷灰石的形成有限。虽然存在一些缺点,但我们认为使用球形颗粒对改善AC的可注射性是非常有用的。因此,寻找合适的方法制备球形粉末作为活性炭的组分具有重要意义。
Apatite cement (AC) can be injected through syringe and forms apatite mass. Therefore, AC is very useful for a minimally invasive surgical operation aimed for the reconstruction of bone defects. However, injectability of current AC is not satisfactory for its clinical use. In this investigation, therefore, spherical tetracalcium phosphate (s-TTCP) was prepared with plasma melting method and its effect on injectability were evaluated as well as other basic properties of AC. We found much better handling property and injectability when we used s-TTCP as a component of AC (s-AC). For example, cement spread area used as an index of consistency of the s-AC paste was 512 mm2 whereas that of ordinary AC with irregular TTCP (i-AC) was 158 mm2 when powder to liquid mixing ratio was 2.5. However, diametral tensile strength of set s-AC (1.4 MPa) was significantly lower than that of set i-AC (10.7 MPa) when the powder to liquid ratio was 4.0. X-ray powder diffraction analysis revealed limited formation of apatite in the case of s-AC. Although there are some drawbacks, we feel the use of spherical particle is very useful to improve the injectability of AC. Therefore, it is important to find suitable method to prepare spherical powder as the component of AC.
DOI: 10.1016/s0142-9612(98)00061-1
发表时间: 1998-08-01
期刊: BIOMATERIALS
影响因子: 14
作者:
Daculsi, G
通讯作者: Daculsi, G