Cyanobacterial contribution to the genomes of the plastid-lacking protists.
Cyanobacterial contribution to the genomes of the plastid-lacking protists.
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DOI：
10.1186/1471-2148-9-197
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发表时间：
2009-08-11
影响因子：
3.4
通讯作者：
Nozaki H
中科院分区：
文献类型：
--
作者：
Maruyama S;Matsuzaki M;Misawa K;Nozaki H
缺乏质体的原生生物中具有蓝藻祖先的真核基因被认为是真核生物早期进化中质体存在的重要进化标记。虽然最近的基因组调查表明，蓝藻和藻类的祖先基因的基因组中的质体缺乏原生生物的存在，这些基因的起源和分布的比较分析仍然是有限的。我们使用一种新的系统发育管道在分类学上广泛的缺乏质体的真核生物（疫霉属[Chromalveolata]、耐格里属[Excavata]、网柄霉属[Amoebozoa]、酵母属和单囊藻属[后孔藻属]）的基因组中鉴定了12个具有蓝藻祖先的基因家族。具有蓝藻祖先的真核基因分支主要由来自双孔目（Archaeplastida、Chromalveolata、Rhizaria和Excavata）的基因组成。除了真菌中保守的光呼吸酶外，我们未能在酵母属和网囊藻属中找到具有蓝藻祖先的基因。同时，我们发现了几个具有蓝藻祖先的Monosiga基因，它们与其他后鞭毛门基因无关。我们的数据表明，相当数量的基因与蓝藻祖先的基因组组成的质体缺乏原生生物，特别是bikonts。这些基因的起源可能是由于横向基因转移事件，或古老的初级或次级内共生之前的bikonts多样化。我们的数据还表明，在这项研究中鉴定的所有基因构成多基因家族与真核生物之间的点状分布，这表明转移的基因可能已经通过轮的基因家族扩增和差异减少生存。
Eukaryotic genes with cyanobacterial ancestry in plastid-lacking protists have been regarded as important evolutionary markers implicating the presence of plastids in the early evolution of eukaryotes. Although recent genomic surveys demonstrated the presence of cyanobacterial and algal ancestry genes in the genomes of plastid-lacking protists, comparative analyses on the origin and distribution of those genes are still limited. We identified 12 gene families with cyanobacterial ancestry in the genomes of a taxonomically wide range of plastid-lacking eukaryotes (Phytophthora [Chromalveolata], Naegleria [Excavata], Dictyostelium [Amoebozoa], Saccharomyces and Monosiga [Opisthokonta]) using a novel phylogenetic pipeline. The eukaryotic gene clades with cyanobacterial ancestry were mostly composed of genes from bikonts (Archaeplastida, Chromalveolata, Rhizaria and Excavata). We failed to find genes with cyanobacterial ancestry in Saccharomyces and Dictyostelium, except for a photorespiratory enzyme conserved among fungi. Meanwhile, we found several Monosiga genes with cyanobacterial ancestry, which were unrelated to other Opisthokonta genes. Our data demonstrate that a considerable number of genes with cyanobacterial ancestry have contributed to the genome composition of the plastid-lacking protists, especially bikonts. The origins of those genes might be due to lateral gene transfer events, or an ancient primary or secondary endosymbiosis before the diversification of bikonts. Our data also show that all genes identified in this study constitute multi-gene families with punctate distribution among eukaryotes, suggesting that the transferred genes could have survived through rounds of gene family expansion and differential reduction.
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影响因子：
12.3
作者：
Huang J;Mullapudi N;Lancto CA;Scott M;Abrahamsen MS;Kissinger JC
通讯作者：
Kissinger JC
影响因子：
3.4
作者：
Maruyama S;Misawa K;Iseki M;Watanabe M;Nozaki H
通讯作者：
Nozaki H
影响因子：
11.6
作者：
Boldt, R;Edner, C;Bauwe, H
通讯作者：
Bauwe, H
影响因子：
2.2
作者：
Adl, SM;Simpson, AGB;Taylor, MFJR
通讯作者：
Taylor, MFJR
影响因子：
5.1
作者：
Gray, J;Wardzala, E;Pauli, F
通讯作者：
Pauli, F