'Image-navigated 3-dimensional late gadolinium enhancement cardiovascular magnetic resonance imaging: feasibility and initial clinical results'.

'Image-navigated 3-dimensional late gadolinium enhancement cardiovascular magnetic resonance imaging: feasibility and initial clinical results'.
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DOI:
10.1186/s12968-017-0418-7
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发表时间:
2017-12-04
期刊:
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子:
--
通讯作者:
Nagel E
Nagel E
中科院分区:
其他
文献类型:
--
作者:
Bratis K;Henningsson M;Grigoratos C;Dell'Omodarme M;Chasapides K;Botnar R;Nagel E

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图像导航的三维晚期Gd增强(iNAV-3D LGE)是一种先进的成像技术,允许对心脏进行直接的呼吸运动校正。它在常规临床环境中的可行性尚未得到验证。23名连续接受心血管磁共振(CMR)检查的患者,包括晚期Gd增强(LGE)成像,被前瞻性纳入其中。在1.5TCMR系统上随机采集图像导航自由呼吸三维(3D)T1加权梯度回波LGE和二维LGE图像。对图像进行全局性、节段性LGE检测和跨壁范围评估。目的评价图像质量,包括信噪比(SNR)、对比噪声比(CNR)和心肌/血液清晰度。在所有2D-LGE和22/23 iNAV-3D LGE检查中都获得了可解释的图像,总共产生了22个数据集和352个节段。缺血型5例,非缺血型7例,缺血型10例。在全局、节段性LGE检测和跨壁检测方面,2D和3D数据集之间有很好的一致性。两种技术之间的血液-心肌锐度测量也具有可比性。2DLGE的SNRred和CNRhemod-myo显著高于2DLGE(P < 0.001),而SNRmyo在2DLGE和iNAV-3DLGE之间无统计学意义。在前瞻性的临床环境中,iNAV-3D LGE的诊断性能与2D LGE相当。INAV-3DLGE组SNRred和CNRhemod-myo显著降低。
Image-navigated 3-dimensional late gadolinium enhancement (iNAV-3D LGE) is an advanced imaging technique that allows for direct respiratory motion correction of the heart. Its feasibility in a routine clinical setting has not been validated. Twenty-three consecutive patients referred for cardiovascular magnetic resonance (CMR) examination including late gadolinium enhancement (LGE) imaging were prospectively enrolled. Image-navigated free-breathing 3-dimensional (3D) T1-weighted gradient-echo LGE and two-dimensional (2D LGE) images were acquired in random order on a 1.5 T CMR system. Images were assessed for global, segmental LGE detection and transmural extent. Objective image quality including signal-to-noise (SNR), contrast-to-noise (CNR) and myocardial/blood sharpness were performed. Interpretable images were obtained in all 2D–LGE and in 22/23 iNAV-3D LGE exams, resulting in a total of 22 datasets and 352 segments. LGE was detected in 5 patients with ischemic pattern, in 7 with non-ischemic pattern, while it was absent in 10 cases. There was an excellent agreement between 2D and 3D data sets with regard to global, segmental LGE detection and transmurality. Blood-myocardium sharpness measurements were also comparable between the two techniques. SNRblood and CNRblood-myo was significantly higher for 2D LGE (P < 0.001, respectively), while SNRmyo was not statistically significant between 2D LGE and iNAV-3D LGE. Diagnostic performance of iNAV-3D LGE was comparable to 2D LGE in a prospective clinical setting. SNRblood and CNRblood-myo was significantly lower in the iNAV-3D LGE group.
基于3D图像的导航剂进行冠状动脉造影术的非辅助运动校正。
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