A Mobile Game for Crowdsourced Molecular Docking Pathways

A Mobile Game for Crowdsourced Molecular Docking Pathways
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众包分子对接途径的手机游戏

DOI:
10.1145/3359566.3360055
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发表时间:
2019
期刊:
Interaction and Games
影响因子:
--
通讯作者:
Jacobson, Bruna
Jacobson, Bruna
中科院分区:
--
文献类型:
--
作者:
Chavez, Anna;Adamson, Torin;Tapia, Lydia;Jacobson, Bruna

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近年来,移动的游戏已经成为一种流行的消遣方式,使其成为通过科学游戏进行众包数据收集的可行途径。我们提出了一个这样的应用程序的科学游戏在移动的设备上通过适应现有的分子对接游戏与适合于这个平台的用户界面。在这项初步研究中,玩家探索分子相互作用的状态空间,并收集数据用于分子运动规划。将结果与从运动规划中常用的自动高斯采样器收集的状态进行比较。玩家能够贡献状态,帮助规划者找到能量低于自动采样器的分子运动路径。然而,由于缺乏分子的灵活性和对探索的指导,玩家在困难区域达到状态的能力仍然存在挑战,而不仅仅是找到最低的能量状态。
Mobile gaming has become a popular pastime in recent years making it a viable avenue for crowdsourcing data collection with scientific games. We present one such application of scientific games on mobile devices by adapting an existing molecular docking game with a user interface suitable for this platform. In this initial study, players explore the state space of molecular interactions, and data is collected to be used in molecular motion planning. The results were compared to states collected from an automated Gaussian sampler commonly used in motion planning. Players were able to contribute states that could aid planners in finding molecular motion pathways with energies lower than the automated sampler. However, there remain challenges to the players’ ability to reach states in difficult areas due to the lack of molecular flexibility and guidance towards exploration over simply finding the lowest energy state.
分子俄罗斯方块:使用路径规划和触觉设备的众包分子对接
DOI: 10.1145/2668084.2668086
发表时间: 2014
期刊: Proceedings of the Seventh International Conference on Motion in Games
影响因子: --
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