Stem cells, multiorgan failure in radiation emergency medical preparedness: a U.S./European Consultation Workshop.
Stem cells, multiorgan failure in radiation emergency medical preparedness: a U.S./European Consultation Workshop.
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DOI：
10.1002/stem.16
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发表时间：
2009-05
期刊：
影响因子：
5.2
通讯作者：
Coleman, C. Norman
中科院分区：
文献类型：
--
作者：
Fliedner, Theodor M.;Chao, Nelson J.;Bader, Judith L.;Boettger, Axel;Case, Cullen, Jr.;Chute, John;Confer, Dennis L.;Ganser, Arnold;Gorin, Norbert-Claude;Gourmelon, Patrick;Graessle, Dieter H.;Krawisz, Robert;Meineke, Viktor;Niederwieser, Dietger;Port, Matthias;Powles, Ray;Sirohi, Bhawna;Weinstock, David M.;Wiley, Albert;Coleman, C. Norman
关键词：
公众对涉及核紧急情况的恐怖主义行动的关切导致重新开始讨论如何以最佳方式科普不可避免的健康损害。美国和欧洲的医学专家认为，必须在国际一级统一对辐射引起的健康损害的诊断和治疗方法。本文件是最近在德国乌尔姆的乌尔姆大学举行的第一次讨论辐射应急准备和援助办法的美国/欧洲协商讲习班的成果。讨论涉及评估全身接触后的损害程度，特别是对造血干细胞库损害的数量和质量。其次，多器官功能衰竭的发病机制被认为是由于器官与器官的相互作用。第三，审议了利用为欧洲共同体制定的“反应类别”办法来协调国际一级使用的“分类方法”的办法。这些讨论导致的结论是，有一个强烈的需要继续教育的医生，护士和支持人员，以解决所提出的问题的管理患有辐射综合征的病人。最后，讨论中表示，需要在研究和开发治疗任何类型放射综合症患者的更完善方法方面开展更多的国际合作。
The concern of the public regarding terrorist actions involving nuclear emergencies resulted in the reopening of the discussion regarding the best ways to cope with the inevitable health impairments. Medical experts from the United States and from Europe considered it of importance to harmonize at an international level the diagnostic and therapeutic approaches regarding the radiation-induced health impairments. The present contribution is the result of the first US/European Consultation Workshop addressing approaches to radiation emergency preparedness and assistance, which was held recently at Ulm University, Ulm, Germany. Discussions dealt with the assessment of the extent of damage after total body exposure and, in particular, the quantity and quality of the damage to the hematopoietic stem cell (HSC) pool. Secondly, the pathogenesis of the multi-organ failure was considered because of the organ-to-organ interactions. Thirdly, approaches were considered to harmonize the “triage-methods” used on an international level using the “Response Category” approach as developed for the European Communities. These discussions lead to the conclusion that there is a strong need for continuing education of physicians, nurses and support personnel to address the issues posed by the management of patients suffering from radiation syndromes. Finally, the discussions expressed the need for more international cooperation in research and development of more refined methods to treat patients with any type of radiation syndromes.
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影响因子：
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