Examining phase contrast sensitivity to signal location and tissue thickness in breast imaging

Examining phase contrast sensitivity to signal location and tissue thickness in breast imaging
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检查乳腺成像中信号位置和组织厚度的相差敏感性

DOI:
10.1117/12.2294968
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发表时间:
2018
期刊:
SPIE Medical Imaging: Physics of Imaging
影响因子:
--
通讯作者:
Das, Mini
Das, Mini
中科院分区:
--
文献类型:
--
作者:
Vespucci, Stefano;Lewis, Cale;Park, Chan-Soo;Das, Mini

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x射线相衬成像(PCI)正在发展,作为克服现有衰减成像技术对比度灵敏度差的替代方法。“相位灵敏度”可以通过使用许多相位增强几何形状来实现,例如自由空间传播,光栅干涉测量和边缘照明(也称为编码孔径)技术。投影强度的增强对比度(结合吸收和相位效应)会因物体形状、尺寸和材料特性以及所使用的特定PCI方法而变化。我们展示了FSP和编码孔径(CA) PCI的信号增强比较。我们的数据表明,与FSP相比,CA的相位增强明显更高。我们的初步结果表明,随着背景厚度的增加,增强相位效应在所有PCI技术中都有所降低。涉及信号位置和背景组织厚度相关的信号增强(和/或信号丢失)的研究对于确定PCI方法在涉及厚器官(如乳腺成像)的实际应用中的真正益处非常重要。
X-Ray phase contrast imaging (PCI) is being developed as an alternative to overcome the poor contrast sensitivity of existing attenuation imaging techniques. The “phase sensitivity” can be achieved using a number of phase-enhancing geometries such as free space propagation, grating interferometry and edge illumination (also known as coded aperture) technique. The enhanced contrast in the projected intensities (that combine absorption and phase effect) can vary by object shape, size and its material properties as well as the particular PCI method used. We show a comparison of this signal enhancement for both FSP and coded aperture (CA) PCI. Our data shows that the phase enhancement is significantly higher for CA in comparison to FSP. Our preliminary results indicate that the enhanced phase effect decreases in all PCI techniques with increasing background thickness. Investigations involving signal location and background tissue thickness dependent signal enhancement (and/or loss of this signal) are very important in determining the true benefit of PCI methods in a practical application involving thick organs like breast imaging.
DOI: 10.1118/1.4820371
发表时间: 2013-10-01
期刊: MEDICAL PHYSICS
影响因子: 3.8
作者:
Taguchi, Katsuyuki;Iwanczyk, Jan S.
通讯作者: Iwanczyk, Jan S.
DOI: 10.1118/1.1593836
发表时间: 2003-08-01
期刊: MEDICAL PHYSICS
影响因子: 3.8
作者:
Wu, XZ;Liu, H
通讯作者: Liu, H