Magnetization-prepared GRASP MRI for rapid 3D T1 mapping and fat/water-separated T1 mapping.
Magnetization-prepared GRASP MRI for rapid 3D T1 mapping and fat/water-separated T1 mapping.
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DOI：
10.1002/mrm.28679
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发表时间：
2021-07
影响因子：
3.3
通讯作者：
Yang Y
中科院分区：
文献类型：
--
作者：
Feng L;Liu F;Soultanidis G;Liu C;Benkert T;Block KT;Fayad ZA;Yang Y
本研究旨在（i）使用快速自由呼吸T1标测的星堆轨迹开发磁化准备黄金角放射性稀疏并行（MP-GRASP）MRI，以及（ii）将MP-GRASP扩展到脂肪/水分离（水特异性）T1标测的多回波采集（MP-Dixon-GRASP）。将绝热非选择性180°反转恢复脉冲添加到基于梯度回波的黄金角星叠序列中，用于磁化准备的3D单回波或3D多回波采集。结合基于子空间的GRASP-Pro重建，该序列分别允许标准T1标测（MP-GRASP）或脂肪/水分离T1标测（MP-Dixon-GRASP）。在体模和志愿者（大脑和肝脏）中，对照临床上可接受的参考方法，评价了使用MP-GRASP进行T1标测的准确性。还在体模和志愿者中评估了T1估计的重复性。在脂肪/水体模和志愿者（大脑和肝脏）中评价了MP-Dixon-GRASP用于水特异性T1标测的性能。在体模（R2 = 1.0）、大脑（R2 = 0.96）和肝脏（R2 = 0.73）中，基于ROI的平均T1值在参考和MP-GRASP之间相关。MP-GRASP在体模（R2 = 1.0）、大脑（R2 = 0.99）和肝脏（R2 = 0.82）中实现了T1估计的良好重复性。在体模和志愿者中，水特异性T1不同于同相和异相复合T1（脂肪和水信号同相或异相混合时的复合T1）。这项工作证明了MP-GRASP和MP-Dixon-GRASP MRI在大脑（无运动）和肝脏（自由呼吸期间）中快速3D T1标测和3D脂肪/水分离T1标测的初始性能。通过脂肪/水分离的T1估计，MP-Dixon-GRASP可能对脂肪肝患者的成像有潜在的帮助。
This study aimed to (i) develop Magnetization-Prepared Golden-angle RAdial Sparse Parallel (MP-GRASP) MRI using a stack-of-stars trajectory for rapid free-breathing T1 mapping and (ii) extend MP-GRASP to multi-echo acquisition (MP-Dixon-GRASP) for fat/water-separated (water-specific) T1 mapping. An adiabatic non-selective 180° inversion-recovery pulse was added to a gradient-echo-based golden-angle stack-of-stars sequence for magnetization-prepared 3D single-echo or 3D multi-echo acquisition. In combination with subspace-based GRASP-Pro reconstruction, the sequence allows for standard T1 mapping (MP-GRASP) or fat/water-separated T1 mapping (MP-Dixon-GRASP), respectively. The accuracy of T1 mapping using MP-GRASP was evaluated in a phantom and volunteers (brain and liver) against clinically accepted reference methods. The repeatability of T1 estimation was also assessed in the phantom and volunteers. The performance of MP-Dixon-GRASP for water-specific T1 mapping was evaluated in a fat/water phantom and volunteers (brain and liver). ROI-based mean T1 values are correlated between the references and MP-GRASP in the phantom (R2 = 1.0), brain (R2 = 0.96), and liver (R2 = 0.73). MP-GRASP achieved good repeatability of T1 estimation in the phantom (R2 = 1.0), brain (R2 = 0.99), and liver (R2 = 0.82). Water-specific T1 is different from in-phase and out-of-phase composite T1 (composite T1 when fat and water signal are mixed in phase or out of phase) both in the phantom and volunteers. This work demonstrated the initial performance of MP-GRASP and MP-Dixon-GRASP MRI for rapid 3D T1 mapping and 3D fat/water-separated T1 mapping in the brain (without motion) and in the liver (during free breathing). With fat/water-separated T1 estimation, MP-Dixon-GRASP could be potentially useful for imaging patients with fatty-liver diseases.
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影响因子：
3.3
作者：
Feng, Li;Grimm, Robert;Block, Kai Tobias;Chandarana, Hersh;Kim, Sungheon;Xu, Jian;Axel, Leon;Sodickson, Daniel K.;Otazo, Ricardo
通讯作者：
Otazo, Ricardo
影响因子：
16.6
作者：
Cloos MA;Knoll F;Zhao T;Block KT;Bruno M;Wiggins GC;Sodickson DK
通讯作者：
Sodickson DK
DOI：
10.1186/s12968-016-0280-z
发表时间：
2016-09-22
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Captur G;Gatehouse P;Keenan KE;Heslinga FG;Bruehl R;Prothmann M;Graves MJ;Eames RJ;Torlasco C;Benedetti G;Donovan J;Ittermann B;Boubertakh R;Bathgate A;Royet C;Pang W;Nezafat R;Salerno M;Kellman P;Moon JC
通讯作者：
Moon JC
影响因子：
3.3
作者：
Haji-Valizadeh, Hassan;Collins, Jeremy D.;Kim, Daniel
通讯作者：
Kim, Daniel
影响因子：
5.9
作者：
Chandarana, Hersh;Block, Kai T.;Milla, Sarah S.
通讯作者：
Milla, Sarah S.