Whole-heart contrast-enhanced coronary magnetic resonance angiography using gradient echo interleaved EPI.
Whole-heart contrast-enhanced coronary magnetic resonance angiography using gradient echo interleaved EPI.
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DOI：
10.1002/mrm.21963
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发表时间：
2009-06
影响因子：
3.3
通讯作者：
Li, Debiao
中科院分区：
文献类型：
--
作者：
Bhat, Himanshu;Zuehlsdorff, Sven;Bi, Xiaoming;Li, Debiao
全心冠状动脉磁共振血管成像（MRA）是一种很有前途的方法来检测冠状动脉疾病。然而，成像时间相对较长（大约10-15分钟）。如此长的成像时间可能导致患者不适，并且由于增加的呼吸和心脏运动伪影而损害全心脏冠状动脉MRA的鲁棒性。本研究的目的是优化梯度回波交错EPI（GRE-EPI）采集方案，以减少对比增强全心脏冠状动脉MRA的成像时间。数值模拟和体模研究被用来优化GRE-EPI序列参数。为了比较的目的，用所提出的GRE-EPI序列和3D TrueFISP序列扫描健康志愿者。Gd-DTPA的缓慢输注（0.5 cc/sec）用于增强GRE-EPI采集的SNR。采用GRE-EPI技术获得全心脏图像，真实分辨率为1.0 × 1.1 × 2.0 mm 3，平均扫描时间为4.7 ± 0.7 min，平均导航效率为44 ± 6%。与TrueFISP采集相比，GRE-EPI采集显示出所有主要冠状动脉的良好描绘，扫描时间缩短了2倍。
Whole-heart coronary magnetic resonance angiography (MRA) is a promising method for detecting coronary artery disease. However, the imaging time is relatively long (on the order of 10–15 minutes). Such a long imaging time may result in patient discomfort and compromise the robustness of whole-heart coronary MRA due to increased respiratory and cardiac motion artifacts. The goal of this study was to optimize a gradient echo interleaved EPI (GRE-EPI) acquisition scheme for reducing the imaging time of contrast-enhanced whole-heart coronary MRA. Numerical simulations and phantom studies were used to optimize the GRE-EPI sequence parameters. Healthy volunteers were scanned with both the proposed GRE-EPI sequence and a 3D TrueFISP sequence for comparison purposes. Slow infusion (0.5 cc/sec) of Gd-DTPA was used to enhance the SNR of the GRE-EPI acquisition. Whole-heart images with the GRE-EPI technique were acquired with a true resolution of 1.0 × 1.1 × 2.0 mm3 in an average scan time of 4.7 ± 0.7 minutes with an average navigator efficiency of 44 ± 6%. The GRE-EPI acquisition showed excellent delineation of all the major coronary arteries with scan time reduced by a factor of 2 compared with the TrueFISP acquisition.
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影响因子：
24
作者：
Sakuma, Hajime;Ichikawa, Yasutaka;Takeda, Kan
通讯作者：
Takeda, Kan
DOI：
10.2463/mrms.6.157
发表时间：
2007-01-01
期刊：
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
影响因子：
--
作者：
Stehning, Christian;Boernert, Peter;Nehrke, Kay
通讯作者：
Nehrke, Kay
影响因子：
3.3
作者：
BRITTAIN, JH;HU, BS;NISHIMURA, DG
通讯作者：
NISHIMURA, DG
影响因子：
3.3
作者：
Griswold, MA;Jakob, PM;Haase, A
通讯作者：
Haase, A
影响因子：
5
作者：
Broome, Dale R.;Girguis, Mark S.;Kirk, Gerald A.
通讯作者：
Kirk, Gerald A.