Vascular Deformation Mapping (VDM) of Thoracic Aortic Enlargement in Aneurysmal Disease and Dissection.
Vascular Deformation Mapping (VDM) of Thoracic Aortic Enlargement in Aneurysmal Disease and Dissection.
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DOI：
10.18383/j.tom.2017.00015
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发表时间：
2017-09
期刊：
影响因子：
--
通讯作者：
Ross BD
中科院分区：
文献类型：
--
作者：
Burris NS;Hoff BA;Kazerooni EA;Ross BD
胸主动脉瘤是一种常见的致命疾病，需要定期进行影像监测，以确定手术修复的时机，并预防破裂等主要并发症。目前的断层图像监测技术主要基于CT血管成像，但这种方法仅限于固定的解剖位置，且容易产生显著的测量误差。在这里，我们提出的初步结果表明，一种新的技术评估主动脉内径变化的可行性，称为血管变形标测(VDM)。这项技术可以通过计算机断层血管成像图像的非刚性配准和主动脉变形的空间雅可比分析来量化主动脉壁几何结构的三维变化。通过几个例证，我们证明了这种方法可以用来测量稳定和扩大的胸主动脉瘤和夹层患者的主动脉壁几何形状的变化。此外，VDM结果提供了常规临床评估不明显的主动脉壁变形的存在、分布和速率的观察结果。最后，我们展示了使用彩色3D打印将患者特定的VDM结果叠加到三维主动脉模型上的可行性，并讨论了VDM技术的未来方向和潜在的应用。
Thoracic aortic aneurysm is a common and lethal disease that requires regular imaging surveillance to determine timing of surgical repair and prevent major complications such as rupture. Current cross-sectional imaging surveillance techniques, largely based on computed tomography angiography, are focused on measurement of maximal aortic diameter, although this approach is limited to fixed anatomic positions and is prone to significant measurement error. Here we present preliminary results showing the feasibility of a novel technique for assessing change in aortic dimensions, termed vascular deformation mapping (VDM). This technique allows quantification of 3-dimensional changes in the aortic wall geometry through nonrigid coregistration of computed tomography angiography images and spatial Jacobian analysis of aortic deformation. Through several illustrative cases we demonstrate that this method can be used to measure changes in the aortic wall geometry among patients with stable and enlarging thoracic aortic aneurysm and dissection. Furthermore, VDM results yield observations about the presence, distribution, and rate of aortic wall deformation that are not apparent by routine clinical evaluation. Finally, we show the feasibility of superposing patient-specific VDM results on a 3-dimensional aortic model using color 3D printing and discuss future directions and potential applications for the VDM technique.
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影响因子：
4.6
作者：
Juvonen, T;Ergin, MA;Griepp, RB
通讯作者：
Griepp, RB
影响因子：
11.3
作者：
Fanelli, Fabrizio;Cannavale, Alessandro;Catalano, Carlo
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Catalano, Carlo
影响因子：
3.3
作者：
Kauffmann, Claude;Tang, An;Soulez, Gilles
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Soulez, Gilles
DOI：
10.12945/j.aorta.2017.17.003
发表时间：
2017-02-01
期刊：
Aorta (Stamford, Conn.)
影响因子：
--
作者：
Brownstein, Adam J;Ziganshin, Bulat A;Elefteriades, John A
通讯作者：
Elefteriades, John A
影响因子：
3.4
作者：
Gagne-Loranger, Maude;Dumont, Eric;Bolotin, G.
通讯作者：
Bolotin, G.