Resveratrol Role in Autoimmune Disease-A Mini-Review.
Resveratrol Role in Autoimmune Disease-A Mini-Review.
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DOI:
10.3390/nu9121306
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发表时间:
2017-12-01
期刊:
影响因子:
5.9
通讯作者:
Monteiro MC
中科院分区:
文献类型:
--
作者:
Oliveira ALB;Monteiro VVS;Navegantes-Lima KC;Reis JF;Gomes RS;Rodrigues DVS;Gaspar SLF;Monteiro MC
Autoimmune diseases are still considered to be pressing concerns due the fact that they are leaders in death and disability causes worldwide. Resveratrol is a polyphenol derived from a variety of foods and beverages, including red grapes and red wine. Anti-inflammatory, antioxidant, and antiaging properties of resveratrol have been reported, and in some animal and human studies this compound reduced and ameliorated the progression of autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and type 1 diabetes mellitus. Thus, this review aims to summarize and critically analyze the role of resveratrol in the modulation of several organ-specific or systemic autoimmune diseases.
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