State‐of‐the‐art paper: Therapeutic hypothermia in out of hospital cardiac arrest survivors

State‐of‐the‐art paper: Therapeutic hypothermia in out of hospital cardiac arrest survivors
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最先进的论文:院外心脏骤停幸存者的治疗性低温

DOI:
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发表时间:
2013
影响因子:
2.3
通讯作者:
C. White
C. White
中科院分区:
医学3区
文献类型:
--
作者:
Mohi E. Alkadri;M. Peters;Morgan J. Katz;C. White

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院外心脏骤停(OHCA)与极低的存活率相关,大多数病例的死亡与神经损伤有关。在出现自主循环恢复(ROSC)的患者中,治疗性低温(TH)是唯一被证实可降低死亡率并改善神经功能预后的干预措施。1958年首次被描述,治疗性低温领域近年来发展迅速。虽然治疗性低温的最新技术进步可能会改善院外心脏骤停幸存者的预后,但仍有几个基本问题有待回答,包括最佳降温速度、哪些患者受益于早期侵入性策略,以及技术进步是否会促进治疗性低温在现场的应用。对治疗性低温策略、设备、监测、技术和并发症的认识和理解的提高,将使这种重要的治疗方式得到更广泛的应用。© 2013威利期刊公司
Out of hospital cardiac arrest (OHCA) is associated with an extremely poor survival rate, with mortality in most cases being related to neurological injury. Among patients who experience return of spontaneous circulation (ROSC), therapeutic hypothermia (TH) is the only proven intervention shown to reduce mortality and improve neurological outcome. First described in 1958, the field of TH has rapidly evolved in recent years. While recent technological advances in TH will likely improve outcomes in OHCA survivors, several fundamental questions remain to be answered including the optimal speed of cooling, which patients benefit from an early invasive strategy, and whether technological advances will facilitate application of TH in the field. An increased awareness and understanding of TH strategies, devices, monitoring, techniques, and complications will allow for a more widespread adoption of this important treatment modality. © 2013 Wiley Periodicals, Inc.
DOI: 10.1016/j.jacc.2010.09.064
发表时间: 2011-02-15
影响因子: 24
作者:
Kong, Melissa H.;Fonarow, Gregg C.;Peterson, Eric D.;Curtis, Anne B.;Hernandez, Adrian F.;Sanders, Gillian D.;Thomas, Kevin L.;Hayes, David L.;Al-Khatib, Sana M.
通讯作者: Al-Khatib, Sana M.
DOI: 10.1152/ajpheart.1996.270.4.h1189
发表时间: 1996-04-01
影响因子: 4.8
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Duncker, DJ;Klassen, CL;Bache, RJ
通讯作者: Bache, RJ