Influence of IOL Weight on Long-Term IOL Stability in Highly Myopic Eyes.

Influence of IOL Weight on Long-Term IOL Stability in Highly Myopic Eyes.
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IOL重量对高度近视眼IOL长期稳定性的影响

DOI:
10.3389/fmed.2022.835475
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发表时间:
2022
影响因子:
3.9
通讯作者:
--
中科院分区:
医学3区
文献类型:
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本研究旨在探讨人工晶状体(IOL)重量对高度近视眼IOL长期稳定性的影响。 本项回顾性研究共纳入205例患者的205只高度近视白内障眼,这些眼分别植入了MC X11 ASP型人工晶状体(A组,86只眼)或920H型人工晶状体(B组,119只眼)。根据IOL度数将患眼分为3个亚组:低度(≥ -5D至<5D)、中度(≥5D至<14D)和高度(≥14D)。术后3年测量IOL偏心、倾斜、高阶像差以及前囊膜开口(ACO)面积,评估IOL重量对IOL长期稳定性的影响。 B组IOL重量显著大于A组(B组与A组相比:(28.31 ± 2.01)mg对(25.71 ± 4.62)mg,P < 0.001)。相应地,B组整体偏心和下方偏心显著大于A组,尤其是在低度和中度IOL度数时(均P < 0.05)。两组中,整体偏心和垂直偏心均与IOL重量显著相关(均P < 0.05)。B组ACO面积显著大于A组(P < 0.05)。多因素分析显示,A组的偏心受IOL重量影响,而B组的偏心受IOL重量和眼轴长度(AL)影响。 较高的IOL重量可能导致高度近视眼IOL长期偏心程度更大,而襻的设计可能在前囊膜收缩中发挥作用。
This study aimed to investigate the influence of intraocular lens (IOL) weight on long-term IOL stability in highly myopic eyes. A total of 205 highly myopic cataract eyes of 205 patients implanted with the MC X11 ASP (Group A, 86 eyes) or 920H IOL (Group B, 119 eyes) were included in this retrospective study. Eyes were divided into 3 subgroups according to the IOL power: low (≥-5 to <5 D), medium (≥5 to <14 D), and high (≥14 D) IOL power. At 3 years after surgery, IOL decentration and tilt, high-order aberrations, and anterior capsular opening (ACO) area were measured. The influence of IOL weight on long-term IOL stability was evaluated. Group B had a significantly greater IOL weight than Group A (Group B vs. Group A: 28.31 ± 2.01 mg vs. 25.71 ± 4.62 mg, P < 0.001). Correspondingly, Group B presented significantly greater overall and inferior decentration than Group A, especially for low and medium IOL power (all P < 0.05). In both groups, overall and vertical decentration was significantly correlated with IOL weight (all P < 0.05). Group B showed a significantly greater ACO area than Group A (P < 0.05). Multivariate analysis showed that decentration in Group A was affected by IOL weight, while decentration in Group B was affected by IOL weight and AL. Higher IOL weight may lead to greater long-term IOL decentration in highly myopic eyes, while the haptic design may play a role in anterior capsular contraction.
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