LSD 2.0: an update of the leaf senescence database.
LSD 2.0: an update of the leaf senescence database.
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DOI：
10.1093/nar/gkt1061
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发表时间：
2014-01
影响因子：
14.9
通讯作者：
Luo J
中科院分区：
文献类型：
--
作者：
Li Z;Zhao Y;Liu X;Peng J;Guo H;Luo J
本手稿描述了 2011 年 NAR 数据库问题中先前介绍的叶子衰老数据库 (LSD) 的更新。 LSD 提供有关衰老相关基因 (SAG) 及其相应突变体的全面信息。我们通过手动和计算方法对这些 SAG 进行了广泛的注释。最近，我们将LSD更新为新版本LSD 2.0（http://www.eplantsenescent.org/），它包含来自44个物种的5356个基因和322个突变体，是之前版本包含来自21个物种的1145个基因和154个突变体的扩展。在当前版本中，我们还包括了几个新功能：（i）添加了基于实验证据检索或设计用于高通量分析的引物序列； (ii) 添加了 100 多张拟南芥 SAG 突变体图像； (iii) 整合了从拟南芥信息资源 (TAIR) 获得的拟南芥种子信息； (iv) 提出了从文献中挖掘或由 SUBA3 程序生成的拟南芥中 SAG 的亚细胞定位信息； (v) 添加了数量性状基因座信息，并附有原始数据库的链接；(vi) 实施了数据库查询的引物和 miRNA 搜索等新选项。更新后的数据库将成为叶片衰老基础研究和农艺重要植物性状操控的宝贵信息资源。
This manuscript describes an update of the leaf senescence database (LSD) previously featured in the 2011 NAR Database Issue. LSD provides comprehensive information concerning senescence-associated genes (SAGs) and their corresponding mutants. We have made extensive annotations for these SAGs through both manual and computational approaches. Recently, we updated LSD to a new version LSD 2.0 (http://www.eplantsenescence.org/), which contains 5356 genes and 322 mutants from 44 species, an extension from the previous version containing 1145 genes and 154 mutants from 21 species. In the current version, we also included several new features: (i) Primer sequences retrieved based on experimental evidence or designed for high-throughput analysis were added; (ii) More than 100 images of Arabidopsis SAG mutants were added; (iii) Arabidopsis seed information obtained from The Arabidopsis Information Resource (TAIR) was integrated; (iv) Subcellular localization information of SAGs in Arabidopsis mined from literature or generated from the SUBA3 program was presented; (v) Quantitative Trait Loci information was added with links to the original database and (vi) New options such as primer and miRNA search for database query were implemented. The updated database will be a valuable and informative resource for basic research of leaf senescence and for the manipulation of traits of agronomically important plants.
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影响因子：
14.9
作者：
Tanz SK;Castleden I;Hooper CM;Vacher M;Small I;Millar HA
通讯作者：
Millar HA
影响因子：
7.2
作者：
Oh, SA;Park, JH;Nam, HG
通讯作者：
Nam, HG
影响因子：
4.4
作者：
Cantu D;Pearce SP;Distelfeld A;Christiansen MW;Uauy C;Akhunov E;Fahima T;Dubcovsky J
通讯作者：
Dubcovsky J
影响因子：
12.3
作者：
Gepstein S
通讯作者：
Gepstein S
影响因子：
7.4
作者：
Sekhon, Rajandeep S.;Childs, Kevin L.;Kaeppler, Shawn M.
通讯作者：
Kaeppler, Shawn M.