Intravital imaging of metastatic behavior through a mammary imaging window.
Intravital imaging of metastatic behavior through a mammary imaging window.
复制标题
DOI:
10.1038/nmeth.1269
复制
发表时间:
2008-12
期刊:
影响因子:
48
通讯作者:
van Rheenen, Jacco
中科院分区:
文献类型:
--
作者:
Kedrin, Dmitriy;Gligorijevic, Bojana;Wyckoff, Jeffrey;Verkhusha, Vladislav V.;Condeelis, John;Segall, Jeffrey E.;van Rheenen, Jacco
We report a technique to evaluate the same tumor microenvironment over multiple intravital imaging sessions in living mice. Individual tumor cells expressing photoswitchable proteins in an orthotopic mammary carcinoma are optically marked and followed for extended times through a Mammary Imaging Window (MIW). We demonstrate, for the first time, that two distinct microenvironments in the same orthotopic mammary tumor affect differently the invasion and intravasation of tumor cells.
登录
查看更多内容
影响因子:
1.5
作者:
Sato, T;Takahoko, M;Okamoto, H
通讯作者:
Okamoto, H
影响因子:
14.8
作者:
Hatta, Kohei;Tsujii, Hitomi;Omura, Tomomi
通讯作者:
Omura, Tomomi
影响因子:
3.5
作者:
Post, JN;Lidke, KA;Arndt-Jovin, DJ
通讯作者:
Arndt-Jovin, DJ
影响因子:
3.5
作者:
Bins, Adriaan D.;van Rheenen, Jacco;Schumacher, Ton N. M.
通讯作者:
Schumacher, Ton N. M.
影响因子:
6
作者:
Lin, EY;Jones, JG;Pollard, JW
通讯作者:
Pollard, JW