Consensus Paper: Towards a Systems-Level View of Cerebellar Function: the Interplay Between Cerebellum, Basal Ganglia, and Cortex.
Consensus Paper: Towards a Systems-Level View of Cerebellar Function: the Interplay Between Cerebellum, Basal Ganglia, and Cortex.
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共识文件：小脑功能的系统级观点：小脑、基底神经节和皮质之间的相互作用。
DOI：
10.1007/s12311-016-0763-3
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发表时间：
2017-02
期刊：
影响因子：
--
通讯作者：
Herreros I
中科院分区：
文献类型：
--
作者：
Caligiore D;Pezzulo G;Baldassarre G;Bostan AC;Strick PL;Doya K;Helmich RC;Dirkx M;Houk J;Jörntell H;Lago-Rodriguez A;Galea JM;Miall RC;Popa T;Kishore A;Verschure PF;Zucca R;Herreros I
尽管越来越多的证据表明小脑与皮层和基底神经节协同工作，但这三个大脑区域之间相互作用的本质仍不清楚。这篇共识性的论文收集了最近关于小脑在小脑-基底神经节-丘脑-皮质系统中在一系列运动和认知功能中所起的各种重要作用的不同观点。本文包括理论和经验贡献，涵盖以下主题：支持人类和其他动物小脑、基底神经节和皮质区之间动态相互作用的最新证据；小脑、基底神经节和皮层在学习和控制过程中相互影响的神经科学理论观点和经验证据数据显示小脑在基底神经节运动障碍中的可能作用。尽管从不同的背景出发，处理不同的主题，但所有的作者都同意，将小脑、基底神经节和皮层视为一个完整的系统，使我们能够以完全不同的方式理解这些区域的功能。此外，作者一致认为，未来的实验和计算工作需要了解小脑-基底神经节回路在运动和非运动功能中的功能。本文报告了小脑在小脑-基底神经节-丘脑-皮质系统中的作用的最先进的观点，并说明了该领域的共识以及分歧和开放问题的其他要素。
Despite increasing evidence suggesting the cerebellum works in concert with the cortex and basal ganglia, the nature of the reciprocal interactions between these three brain regions remains unclear. This consensus paper gathers diverse recent views on a variety of important roles played by the cerebellum within the cerebello-basal ganglia-thalamo-cortical system across a range of motor and cognitive functions. The paper includes theoretical and empirical contributions, which cover the following topics: recent evidence supporting the dynamical interplay between cerebellum, basal ganglia, and cortical areas in humans and other animals; theoretical neuroscience perspectives and empirical evidence on the reciprocal influences between cerebellum, basal ganglia, and cortex in learning and control processes; and data suggesting possible roles of the cerebellum in basal ganglia movement disorders. Although starting from different backgrounds and dealing with different topics, all the contributors agree that viewing the cerebellum, basal ganglia, and cortex as an integrated system enables us to understand the function of these areas in radically different ways. In addition, there is unanimous consensus between the authors that future experimental and computational work is needed to understand the function of cerebellar-basal ganglia circuitry in both motor and non-motor functions. The paper reports the most advanced perspectives on the role of the cerebellum within the cerebello-basal ganglia-thalamo-cortical system and illustrates other elements of consensus as well as disagreements and open questions in the field.
影响因子：
2.7
作者：
Carrel, Andrew J.;Zbarska, Svitlana;Zenitsky, Gary D.;Bracha, Vlastislav
通讯作者：
Bracha, Vlastislav