Optimisation of GraPhage13 macro-dispersibility via understanding the pH-dependent ionisation during self-assembly: towards the manufacture of graphene-based nanodevices.
Optimisation of GraPhage13 macro-dispersibility via understanding the pH-dependent ionisation during self-assembly: towards the manufacture of graphene-based nanodevices.
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DOI：
10.1039/d3nr00778b
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发表时间：
2023-08-17
期刊：
影响因子：
6.7
通讯作者：
Oppenheimer, Pola Goldberg
中科院分区：
文献类型：
--
作者：
Stokes, Kate;Sun, Yiwei;Passaretti, Paolo;White, Henry;Oppenheimer, Pola Goldberg
GraPhage 13气凝胶（GPAs）是通过氧化石墨烯（GO）和M13噬菌体自组装产生的微孔结构。由于GPA制造涉及GO和M13在水溶液中的聚集，我们的目标是了解其在宽pH范围内的稳定性。在此，已经开发了一种新的技术，将官能团的电离与表面电荷联系起来，从而深入了解GPA制造所需的条件及其自组装背后的机制。在pH 2-6之间观察到GO和M13的聚集，并且表现出对所得聚集体的表面电荷的依赖性，其中M13噬菌体被鉴定为对此有贡献的主要因素，同时源自其官能团的电离。相比之下，GO由于其羧基、烯醇和酚官能团在pH 6及以上的去质子化而对表面电荷表现出较小的影响，这福尔斯落在聚集所需的pH范围之外。这些结果增强了我们对GPA自组装机制、其制造所需条件和最佳加工性能的理解，为其广泛的应用和后续基于石墨烯的纳米器件的制造奠定了基础。GraPhage 13气凝胶（GPAs）是通过氧化石墨烯（GO）和M13噬菌体自组装产生的微孔结构。
GraPhage13 aerogels (GPAs) are micro-porous structures generated through the self-assembly of graphene oxide (GO) and M13 bacteriophage. As GPA fabrication involves the aggregation of GO and M13 in aqueous solution, we aim to understand its dispersibility across a wide pH range. Herein, a novel technique has been developed to relate the ionisation of functional groups to the surface charge, offering insights into the conditions required for GPA fabrication and the mechanism behind its self-assembly. The aggregation of GO and M13 was observed between pH 2–6 and exhibited dependence on the surface charge of the resulting aggregate with the M13 bacteriophage identified as the primary factor contributing to this, whilst originating from the ionisation of its functional groups. In contrast, GO exhibited a lesser impact on the surface charge due to the deprotonation of its carboxylic, enolic and phenolic functional groups at pH 6 and above, which falls outside the required pH range for aggregation. These results enhance our understanding of the GPA self-assembly mechanism, the conditions required for their fabrication and the optimal processability, laying the foundation towards its broad range of applications and the subsequent manufacture of graphene-based nanodevices. GraPhage13 aerogels (GPAs) are micro-porous structures generated through the self-assembly of graphene oxide (GO) and M13 bacteriophage.
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