HEC-1 Cells: Establishment of an In Vitro Experimental System in Endometrial Carcinoma

HEC-1 Cells: Establishment of an In Vitro Experimental System in Endometrial Carcinoma
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HEC-1细胞:子宫内膜癌体外实验体系的建立

DOI:
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发表时间:
2003
期刊:
影响因子:
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通讯作者:
M. Kawaguchi
M. Kawaguchi
中科院分区:
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文献类型:
--
作者:
H. Kuramoto;M. Hamano;M. Imai;T. Fujisawa;Y. Kamata;T. Arai;M. Kawaguchi

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HEC-1细胞系是人类子宫内膜腺癌的第一个体外细胞系,使我们能够在简化的细胞系统水平上开展子宫内膜和子宫内膜癌的研究工作,为子宫内膜癌的细胞和分子生物学研究做出贡献。一旦建立了细胞系,它就提供了一个稳定的实验系统,促进和推进了对细胞系来源的组织和/或肿瘤的研究。在这篇文章中,我们报告了HEC-1细胞是如何建立的,并清除了建议的要求,以表征已建立的细胞系。此外,为了证明细胞系一旦建立后在研究工作中的用处,我们通过回顾使用HEC-1和HEC家族子宫内膜癌细胞所获得的结果来说明这些概念,并回顾了关于使用这些细胞所取得的成果的文献。
The HEC-1 cell line was the first in vitro cell line of a human endometrial adenocarcinoma, which enabled us to perform research work on the endometrium and endometrial carcinoma at the level of a simplified cellular system; contributing to cell and molecular biological studies on endometrial carcinoma. Once a cell line is established, it provides a stable experimental system that facilitates and progresses the study of the tissues and/or neoplasias from which the cell line is derived. In this article, we report how HEC-1 cells have been established and cleared the proposed requirements to characterize an established cell line. In addition, in order to demonstrate the usefulness of the cell lines for research work once they have been established, we illustrate these concepts by recalling results obtained with HEC-1 and the HEC family of endometrial carcinoma cells and review the literature with regard to what has been achieved by using these cells.
培养的人子宫内膜上皮细胞和基质细胞中的雌激素受体。
DOI: 10.1016/0022-4731(80)90266-6
发表时间: 1980
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影响因子: --
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雌激素无反应的人子宫内膜腺癌细胞中雌激素受体系统的改变。
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DOI: --
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DOI: 10.1016/0090-8258(88)90030-3
发表时间: 1988-06
影响因子: 4.7
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通讯作者: Seija E. Grenman;James A. Roberts;Barry G. England;Matti Grönroos;Thomas E. Carey
DOI: --
发表时间: 1990-06
期刊: Cancer research
影响因子: 11.2
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