Histochemical evidence of limited reinnervation of human corneal grafts
Histochemical evidence of limited reinnervation of human corneal grafts
复制标题
人角膜移植物有限神经支配的组织化学证据
DOI：
10.1111/j.1755-3768.1985.tb01535.x
复制
发表时间：
1985
影响因子：
3.4
通讯作者：
B. Holden
中科院分区：
文献类型：
--
作者：
T. Tervo;A. Vannas;K. Tervo;B. Holden
抽象的。在正常人角膜和再移植后获得的 3 个角膜移植物中，组织化学显示乙酰胆碱酯酶 (AChE) 阳性神经纤维。在正常角膜中，AChE 阳性神经形成基质神经束，基质神经束分为更小的分支，形成基底上皮神经丛。上皮内末端是该神经丛的分支。在手术后 29 年获得的移植角膜中，上皮由基底上皮丛神经支配，但尽管术后时间很长，但只有少数基质神经干再生。在这种情况下，角膜敏感性尚未恢复正常。剩余的移植物是在手术后不到 3 年获得的，含有很少的神经。移植角膜中角膜神经的结构和密度似乎都没有完全再生，这可能解释了为什么敏感性没有恢复正常。
Abstract. Acetylcholinesterase (AChE) positive nerve fibers were demonstrated histochemically in the normal human cornea and in 3 corneal grafts obtained after retransplantation. In the normal cornea AChE positive nerves form stromal nerve bundles, which divide into smaller branches contributing to the basal epithelial nerve plexus. Intraepithelial terminals are branches of this plexus. In a grafted cornea obtained 29 years after surgery the epithelium was innervated by a basal epithelial plexus, but only a few stromal nerve trunks had regenerated despite the long post‐operative time. Corneal sensitivity had not returned to normal in this case. The remaining grafts, obtained less than 3 years after surgery, contained very few nerves. It seems that neither the architecture nor the density of corneal nerves fully regenerate in the graft cornea, and this probably explains why sensitivity does not return to normal.
影响因子：
4.4
作者：
A. J. Rózsa;R. B. Guss;R. Beuerman
通讯作者：
A. J. Rózsa;R. B. Guss;R. Beuerman