Response to "Right Analysis-Wrong Conclusion: Obese Youth With Higher BP Are at Risk for Target Organ Damage".
Response to "Right Analysis-Wrong Conclusion: Obese Youth With Higher BP Are at Risk for Target Organ Damage".
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回应“正确的分析 - 错误的结论：血压较高的肥胖青少年面临靶器官损伤的风险”。
DOI：
10.1093/ajh/hpv085
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发表时间：
2015
影响因子：
3.2
通讯作者：
Haas,GerdaM
中科院分区：
文献类型：
--
作者：
Schwandt,Peter;Scholze,JuergenE;Bertsch,Thomas;Ecotroph,EvelynL;Haas,GerdaM
致编辑：我们非常感谢乌尔比纳博士和福克纳博士对我们在青少年血压百分位数方面的贡献所作的令人振奋的评论《正确的分析-错误的结论》。我们承认他们“同意肥胖青年的平均血压水平较高，但这不应该被‘原谅’，而是应该进行评估和管理。”我们同意没有儿童高血压的结局数据，因此没有临床阈值，只有血压和临床前器官损害之间的关联。毫无疑问，应根据既定的指导方针尽早发现和消除危险因素。然而，必须考虑整体肥胖和腹部肥胖的独立贡献3此外，尽管Bogalusa心脏研究中肥胖增加，但收缩压（SBP）或舒张压（DBP）水平没有增加4，英国儿童在过去30年中收缩压增加，但体重指数的平行增加仅解释了收缩压增加的15%。5
To the Editor: We thank Drs Urbina and Falkner very much for their stimulating commentary “Right Analysis—Wrong Conclusion” 1 to our contribution on blood pressure (BP) percentiles in youth. 2 We acknowledge that they “agreed that BP levels on average are higher in obese youth, but these should not be “forgiven” but rather, they should be evaluated and managed.” We agree that there is no outcome data for pediatric hypertension and therefore no clinical threshold, but only associations between BP and preclinical organ damage. There is no doubt that risk factors should be detected and eliminated as early as possible according to the established guidelines. However, an independent contribution of overall and abdominal obesity has to be considered 3 Furthermore, despite increases in obesity in the Bogalusa Heart Study there was no increase in systolic BP (SBP) or diastolic BP (DBP) levels 4 and in UK children SBP increased in the past 3 decades, but the parallel increase of body mass index explains only 15% of SBP increase. 5
影响因子：
4.9
作者：
Peters, Helen;Whincup, Peter H.;Li, Leah
通讯作者：
Li, Leah
影响因子：
3.2
作者：
Schwandt, Peter;Scholze, Juergen E.;Haas, Gerda M.
通讯作者：
Haas, Gerda M.
正确的分析-错误的结论：血压较高的肥胖青少年存在靶器官损伤的风险。
影响因子：
3.2
作者：
Urbina,ElaineM;Falkner,Bonita
通讯作者：
Falkner,Bonita