Superficial Slow Rhythms Integrate Cortical Processing in Humans.
Superficial Slow Rhythms Integrate Cortical Processing in Humans.
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DOI：
10.1038/s41598-018-20662-0
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发表时间：
2018-02-01
影响因子：
4.6
通讯作者：
Halgren E
中科院分区：
文献类型：
--
作者：
Halgren M;Fabó D;Ulbert I;Madsen JR;Erőss L;Doyle WK;Devinsky O;Schomer D;Cash SS;Halgren E
新皮层由六个解剖学和生理学上专门化的层组成。有人提出，整合的活动跨皮层区域介导的解剖学上的关联连接终止于表层，和生理学上的缓慢的皮层节奏。然而，通过新皮层解剖学和生理学相互作用来协调神经活动的方法仍然不清楚。在19名人类参与者中使用层状微电极阵列，我们发现大多数EEG活动低于10 Hz（delta/theta），并且在清醒和睡眠期间由表层皮层产生。皮质表面网格，网格层，和双层录音表明，这些缓慢的节奏是同步的上层广泛的皮质区。这种表面缓慢活动的相位被不频繁的刺激重置，并与所有层的更快振荡和神经元放电的幅度相耦合。这些研究结果支持了浅表慢节奏在产生EEG和整合皮质活动中的主要作用。
The neocortex is composed of six anatomically and physiologically specialized layers. It has been proposed that integration of activity across cortical areas is mediated anatomically by associative connections terminating in superficial layers, and physiologically by slow cortical rhythms. However, the means through which neocortical anatomy and physiology interact to coordinate neural activity remains obscure. Using laminar microelectrode arrays in 19 human participants, we found that most EEG activity is below 10-Hz (delta/theta) and generated by superficial cortical layers during both wakefulness and sleep. Cortical surface grid, grid-laminar, and dual-laminar recordings demonstrate that these slow rhythms are synchronous within upper layers across broad cortical areas. The phase of this superficial slow activity is reset by infrequent stimuli and coupled to the amplitude of faster oscillations and neuronal firing across all layers. These findings support a primary role of superficial slow rhythms in generating the EEG and integrating cortical activity.
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影响因子：
16.2
作者：
Kajikawa Y;Schroeder CE
通讯作者：
Schroeder CE
DOI：
10.1073/pnas.1011284108
发表时间：
2011-07-05
影响因子：
11.1
作者：
Buffalo, Elizabeth A.;Fries, Pascal;Desimone, Robert
通讯作者：
Desimone, Robert
影响因子：
3.2
作者：
Fell, J;Dietl, T;Fernández, G
通讯作者：
Fernández, G
影响因子：
5.7
作者：
Arnulfo, Gabriele;Hirvonen, Jonni;Palva, J. Matias
通讯作者：
Palva, J. Matias
影响因子：
5.3
作者：
Kole, MHP;Hallermann, S;Stuart, GJ
通讯作者：
Stuart, GJ