Effects of mild physical exercise on serum lipoproteins and metabolites of arachidonic acid: a controlled randomised trial in middle aged men.

Effects of mild physical exercise on serum lipoproteins and metabolites of arachidonic acid: a controlled randomised trial in middle aged men.
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轻度体育锻炼对血清脂蛋白和花生四烯酸代谢物的影响:一项针对中年男性的随机对照试验。

DOI:
10.1136/bmj.288.6417.603
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发表时间:
1984
期刊:
British Medical Journal (Clinical research ed.)
影响因子:
--
通讯作者:
J. Huttunen
J. Huttunen
中科院分区:
--
文献类型:
--
作者:
R. Rauramaa;J. Salonen;K. Kukkonen;K. Seppänen;E. Seppälä;H. Vapaatalo;J. Huttunen

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为研究体育锻炼对缺血性心脏病生化危险因素的影响,在一项随机试验中,31名健康中年男子进行了为期两个月的定期体育锻炼,29名作为对照。与对照组相比,定期锻炼的男性血清胆固醇浓度在高密度脂蛋白亚组分2(HDL 2)中增加了26%,在亚组分3(HDL 3)中减少了31%,在低密度脂蛋白组分中减少了9%。在规律运动期间,发现血浆6-酮-前列腺素F1 α浓度有增加和血清血栓素B2浓度降低的趋势,但前列腺素E2浓度保持不变。在定期运动组中,血浆6-酮-前列腺素F1 α浓度的增加与血清HDL 2胆固醇浓度的增加相关。我们的数据表明,温和的定期体育锻炼对健康中年男性血清脂蛋白中胆固醇的分布有有利的影响,并可能对花生四烯酸的循环代谢产物有有益的影响。
To study the effects of physical exercise on biochemical risk factors for ischaemic heart disease 31 healthy middle aged men undertook regular physical exercise for two months and 29 served as controls in a randomised trial. In the men taking regular exercise serum cholesterol concentrations increased 26% more in the high density lipoprotein subfraction two (HDL2) and decreased 31% more in the subfraction three (HDL3) and 9% more in the low density lipoprotein fraction than in the control group. A tendency towards increased plasma 6-keto-prostaglandin F1 alpha concentration and decreased serum thromboxane B2 concentration was found during the period of regular exercise, but prostaglandin E2 concentrations remained unchanged. The increase in plasma 6-keto-prostaglandin F1 alpha concentration was associated with an increase in serum HDL2 cholesterol concentration in the group taking regular exercise. Our data suggest that mild regular physical exercise favourably influences cholesterol distribution in serum lipoproteins in healthy middle aged men and may have beneficial effects on circulating metabolites of arachidonic acid.
DOI: 10.1016/s0021-9258(18)34477-6
发表时间: 1982-06
期刊: The Journal of biological chemistry
影响因子: --
作者:
L. Fleisher;A. Tall;L. Witte;R. Miller;P. Cannon
通讯作者: L. Fleisher;A. Tall;L. Witte;R. Miller;P. Cannon
增加运动水平和血浆脂蛋白浓度:一项针对久坐的中年男性的为期一年的随机对照研究。
DOI: 10.1016/0026-0495(83)90152-x
发表时间: 1983
期刊: Metabolism: clinical and experimental
影响因子: --
作者:
Wood,PD;Haskell,WL;Blair,SN;Williams,PT;Krauss,RM;Lindgren,FT;Albers,JJ;Ho,PH;Farquhar,JW
通讯作者: Farquhar,JW