Relationship between mechanical properties (shear modulus and viscosity), age, and sex in uninjured Achilles tendons.
Relationship between mechanical properties (shear modulus and viscosity), age, and sex in uninjured Achilles tendons.
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DOI：
10.1002/tsm2.148
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发表时间：
2020-07
影响因子：
1.2
通讯作者：
Silbernagel KG
中科院分区：
文献类型：
--
作者：
Sprague AL;Awokuse D;Pohlig RT;Cortes DH;Silbernagel KG
肌腱的力学性能已被提出作为肌腱健康的生物标志物，以跟踪对损伤和治疗的反应。在受伤人群中使用这些属性之前，了解这些属性如何受到未受伤人群中年龄和性别的影响至关重要。回顾性分析了118例未受伤的跟腱，以评估肌腱力学性能与年龄和性别之间的关系。使用连续剪切波弹性成像评估机械性能（剪切模量和粘度）。在调整体重指数和体力活动水平后，完成了一项调节回归分析，以检查肌腱力学性能、年龄和性别之间的关系。剪切模量的年龄和性别之间存在相互作用（p=0.049，R2变化=0.034）。女性的年龄与剪切模量呈负相关（p=0.030，β=-0.350），但在男性中未观察到相关性（p=0.78，β=0.031）。年龄与粘度呈正相关（p=0.034，β=0.214）。粘度增加与年龄增加有关，性别间无差异。老化对剪切模量的影响在男性和女性之间存在差异，这可能有助于解释性别特异性损伤风险及其对机械负荷的不同反应。
Tendon mechanical properties have been proposed as a biomarker of tendon health to track response to injury and treatment. Prior to utilizing these properties in an injured population, it is critical to understand how these are influenced by age and sex in an uninjured population. A retrospective analysis was conducted of 118 uninjured Achilles tendons to evaluate the relationship between tendon mechanical properties, age and sex. Mechanical properties (shear modulus and viscosity) were assessed using continuous shear wave elastography. A moderator regression analysis was completed to examine the relationship between tendon mechanical properties, age and sex, after adjusting for body mass index and physical activity level. There was an interaction between age and sex for shear modulus (p=0.049, R2 change=0.034). Females had a negative relationship between age and shear modulus (p=0.030, β=−0.350) but no relationship was observed for males (p=0.78, β=0.031). A positive relationship was found between age and viscosity (p=0.034, β=0.214). Increased viscosity was related to increased age with no difference between sexes. The effect of aging on shear modulus differed between men and women and may help explain sex specific injury risks and their differing response to mechanical load.
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影响因子：
3.3
作者：
Couppe, Christian;Svensson, Rene Bruggebusch;Magnusson, Stig Peter
通讯作者：
Magnusson, Stig Peter
影响因子：
3.8
作者：
LaCroix, Andrew S.;Duenwald-Kuehl, Sarah E.;Brickson, Stacey;Akins, Tiffany L.;Diffee, Gary;Aiken, Judd;Vanderby, Ray, Jr.;Lakes, Roderic S.
通讯作者：
Lakes, Roderic S.
影响因子：
6.3
作者：
Kongsgaard, M.;Reitelseder, S.;Magnusson, S. P.
通讯作者：
Magnusson, S. P.
DOI：
10.1002/art.24518
发表时间：
2009-06-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Gaida, James E.;Ashe, Maureen C.;Cook, Jill L.
通讯作者：
Cook, Jill L.
影响因子：
5.5
作者：
Maganaris, CN;Paul, JP
通讯作者：
Paul, JP