Factors predicting home medication management practices among chronically ill older population of selected districts of Nepal
Factors predicting home medication management practices among chronically ill older population of selected districts of Nepal
复制标题
尼泊尔选定地区慢性病老年人家庭药物管理实践的预测因素
作者：
S. Shrestha;R. Poudel;S. Pradhan;Aashutosh Adhikari;Arjun Giri;A. Poudel
研究背景老年人的用药需求往往是复杂多样的，因此面临着多种用药、药物不良反应和药物相互作用的挑战。我们的目的是确定家庭用药管理的做法（MMP）及其相关因素之间的慢性病老年人口的选定districts of Nepal.MethodsA社区为基础的横断面调查进行了386慢性病老年人从选定地区的尼泊尔4月至2016年9月之间。采用访谈法，通过问卷评分评估MMP的适当性。多变量Logistic回归分析使用潜在的变量从双变量分析，以确定影响因素MMP.ResultsThe整体家庭MMP大多是不适当的（80.1%）。大多数参与者有单一疾病的多个处方（202，52.3%）和不适当的药物储存（188，48.7%）。虽然大多数患者（378例，97.9%）有给药时间表，但也使用过期药物（2例，0.5%）。回归分析显示，病程小于1年（比值比[OR] = 3.901，95%置信区间[CI] = 1.528至9.959，P = 0.004），病程1-2年（OR = 2.415，95%CI = 1.210 ~ 4.821，P = 0.012）（OR = 2.025，95%CI = 1.036 ~ 3.956，P = 0.039）结论老年慢性病患者的家庭最低生活保障水平与病程、吸烟状况有关生活在尼泊尔选定地区的患者。可能需要对这类病人进行适当的咨询和监测，以改善这种做法。
BackgroundOlder population often have multiple and complex needs that are consequently challenged by the presence of polypharmacy, adverse drug reactions and drug-drug interaction. We aimed to determine home medication management practices (MMP) and its associated factors among chronically ill older population of selected districts of Nepal.MethodsA community based cross-sectional survey was conducted among 386 chronically ill older individuals from selected areas of Nepal between April to September 2016. Appropriateness of MMP was assessed through scores of questions using interview method. Multivariate logistic regression analysis using potential variables from bivariate analysis were used to determine factors affecting MMP.ResultsThe overall home MMP was mostly inappropriate (80.1%). Most participants had multiple prescribers for single disease (202, 52.3%) and inappropriate medication storage (188, 48.7%). Though the majority of them had drug administration schedule (378, 97.9%), expired medicines were also used (2, 0.5%). Regression analysis showed less than one year duration of disease (odds ratio [OR] = 3.901, 95% confidence interval [CI] = 1.528 to 9.959, P = 0.004), 1–2 years duration of disease (OR = 2.415, 95% CI = 1.210 to 4.821, P = 0.012) and smokers (OR = 2.025, 95% CI = 1.036 to 3.956, P = 0.039) as the major factors affecting appropriate home MMP.ConclusionsThe home MMP was associated with duration of disease and smoking status among chronically ill older patients living in selected districts of Nepal. Proper counselling and monitoring of such patients might be necessary to improve the practice.
影响因子：
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作者：
Sabia, Severine;Elbaz, Alexis;Dugravot, Aline;Head, Jenny;Shipley, Martin;Hagger-Johnson, Gareth;Kivimaki, Mika;Singh-Manoux, Archana
通讯作者：
Singh-Manoux, Archana