Diagnosis of lymphoma, leukemia, and metastatic tumor involvement of the cerebrospinal fluid by cytology and immunocytochemistry
Diagnosis of lymphoma, leukemia, and metastatic tumor involvement of the cerebrospinal fluid by cytology and immunocytochemistry
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通过细胞学和免疫细胞化学诊断淋巴瘤、白血病和脑脊液转移性肿瘤
DOI：
10.1002/dc.2840120105
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发表时间：
1995
影响因子：
1.3
通讯作者：
L. Skoog
中科院分区：
文献类型：
--
作者：
E. Tani;I. Costa;E. Svedmyr;L. Skoog
对来自 42 名疑似脑膜肿瘤受累患者的 55 份脑脊液 (CSF) 标本进行了检查。细胞学结合免疫细胞化学鉴定出 26 份脑脊液标本为恶性。其中有 15 例淋巴瘤、4 例白血病、2 例癌症和 2 例黑色素瘤。 11 例 B 细胞淋巴瘤中有 9 例显示单克隆轻链表达。三种 T 细胞淋巴瘤均表达泛 T 标记物 (CD 3) 和两种 T 辅助抗原 (CD 4)。一名患者脑膜受累为真正的组织细胞淋巴瘤，其特征是其大的非典型细胞呈 α-1-抗胰蛋白酶和胞壁质酶阳性。在 4 名初步诊断为急性淋巴细胞白血病的患者中，通过显示具有 CD 10 (cALLA) 或轻链限制的母细胞证实了脑脊液受累。其余四名患者的脑脊液中的肿瘤细胞上显示出上皮细胞或黑素细胞标记。
Fifty‐five cerebrospinal fluid (CSF) specimens from 42 patients with suspected meningeal tumor involvement were reviewed. Cytology in conjunction with immunocytochemistry identified 26 CSF specimens as malignant. There were fifteen cases of lymphoma, four cases of leukemia, two cases of carcinoma, and two cases of melanoma. A monoclonal light chain expression was demonstrated in nine out of eleven B cell lymphomas. the three T‐cell lymphomas all expressed pan T markers (CD 3) and two the T‐helper antigen (CD 4). One patient had meningeal involvement of a true histiocytic lymphoma which was indentified by its large atypical cells which were positive for α‐1‐anti‐trypsin and muramidase. in four patients with a primary diagnosis of acute lymphoblastic leukemia, CSF involvement was confirmed by the demonstration of blasts with CD 10 (cALLA) or light chain restriction. Epithelial or melanocytic markers were demonstrated on the tumor cells in CSF from the remaining four patients.
外周 T 细胞淋巴瘤的细针抽吸细胞学检查。
影响因子：
3.5
作者：
Katz,RL;Gritsman,A;Cabanillas,F;Fanning,CV;Dekmezian,R;Ordonez,NG;Barlogie,B;Butler,JJ
通讯作者：
Butler,JJ
淋巴细胞标记物研究在诊断细胞病理学中的价值。
影响因子：
1.8
作者：
Robey,SS;Cafferty,LL;Beschorner,WE;Gupta,PK
通讯作者：
Gupta,PK