Decision salience signals in posterior cingulate cortex.
Decision salience signals in posterior cingulate cortex.
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DOI：
10.3389/fnins.2011.00055
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发表时间：
2011
影响因子：
4.3
通讯作者：
Platt ML
中科院分区：
文献类型：
--
作者：
Heilbronner SR;Hayden BY;Platt ML
Despite its phylogenetic antiquity and clinical importance, the posterior cingulate cortex (CGp) remains an enigmatic nexus of attention, memory, motivation, and decision making. Here we show that CGp neurons track decision salience – the degree to which an option differs from a standard – but not the subjective value of a decision. To do this, we recorded the spiking activity of CGp neurons in monkeys choosing between options varying in reward-related risk, delay to reward, and social outcomes, each of which varied in level of decision salience. Firing rates were higher when monkeys chose the risky option, consistent with their risk-seeking preferences, but were also higher when monkeys chose the delayed and social options, contradicting their preferences. Thus, across decision contexts, neuronal activity was uncorrelated with how much monkeys valued a given option, as inferred from choice. Instead, neuronal activity signaled the deviation of the chosen option from the standard, independently of how it differed. The observed decision salience signals suggest a role for CGp in the flexible allocation of neural resources to motivationally significant information, akin to the role of attention in selective processing of sensory inputs.
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影响因子：
9.2
作者：
Klein, Jeffrey T.;Deaner, Robert O.;Platt, Michael L.
通讯作者：
Platt, Michael L.
DOI：
10.1073/pnas.0308627101
发表时间：
2004-03-30
影响因子：
11.1
作者：
Greicius, MD;Srivastava, G;Menon, V
通讯作者：
Menon, V
DOI：
10.1523/jneurosci.5742-09.2010
发表时间：
2010-04-21
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Louie K;Glimcher PW
通讯作者：
Glimcher PW
影响因子：
4.8
作者：
Maddock, RJ;Garrett, AS;Buonocore, MH
通讯作者：
Buonocore, MH
影响因子：
9.2
作者：
Deaner, RO;Khera, AV;Platt, ML
通讯作者：
Platt, ML