Plasma-polyplumbagin-modified microfiber probes: a functional material approach to monitoring vascular access line contamination.

Plasma-polyplumbagin-modified microfiber probes: a functional material approach to monitoring vascular access line contamination.
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等离子体聚白花丹素改性微纤维探针:一种监测血管通路污染的功能材料方法。

DOI:
10.1021/am402821c
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发表时间:
2013
影响因子:
9.5
通讯作者:
Davis J
Davis J
中科院分区:
材料科学2区
文献类型:
--
作者:
Davis J

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大气等离子体处理的碳纤维丝(10微米)被用作设计用于血管内接入装置的探头的基底。微纤维探针进一步用聚白花丹素层功能化,通过该层可以伏安法测定线pH,并且其中提供了获得与线的细菌定殖相关的诊断信息的可能性。归因于固定化聚合物的氧化还原过程的特征在于和开发的方法,使收购的氧化还原信号,是选择性的和敏感的pH值。证明了通过检查在全血中的直接响应的复合探针的适用性。
Atmospheric plasma treated carbon fiber filaments (10 micrometer) were used as the base substrate in the design of a probe intended for use within intravascular access devices. The microfiber probe was further functionalized with a polyplumbagin layer through which the line pH could be determined voltammetrically and therein provide the potential for obtaining diagnostic information relating to bacterial colonization of the line. The redox processes attributed to the immobilized polymer are characterized and a methodology developed to enable the acquisition of a redox signal that is selective and sensitive to pH. The applicability of the composite probe was demonstrated through examining the direct response in whole blood.
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