Synthetic genetic circuits in crop plants.
Synthetic genetic circuits in crop plants.
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DOI:
10.1016/j.copbio.2017.07.003
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发表时间:
2018-03
影响因子:
7.7
通讯作者:
Nemhauser J
中科院分区:
文献类型:
--
作者:
de Lange O;Klavins E;Nemhauser J
The love affair between crop breeding and genetics began over a century ago and has continued unabated, from mass selection programs up to the latest techniques for targeted manipulation of genomes. Genetic circuits, combining both regulatory and coding sequences, could accelerate crop improvement. In the near future, complex traits could be rationally designed from genetic components and delivered directly to a genome of interest. However, there is not yet a standardized pipeline from exploratory laboratory testing to crop trials, and bringing transgenic products to market remains a considerable barrier. We highlight successes so far and future developments necessary to make genetic circuits a viable crop improvement technology over this century.
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