The frequent and underrecognised co-occurrence of acute exacerbated COPD and depression warrants screening: a systematic review.

The frequent and underrecognised co-occurrence of acute exacerbated COPD and depression warrants screening: a systematic review.
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DOI:
10.1183/16000617.0026-2017
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发表时间:
2017-06-30
期刊:
European respiratory review : an official journal of the European Respiratory Society
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其他
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患有急性加重慢性阻塞性肺疾病(AECOPD)并并发抑郁症的患者承受着显着的心理压力和生活质量下降。本研究的目的是整理出版物中有关 AECOPD 住院患者抑郁情绪障碍筛查和管理的数据、指南和建议。我们系统地检索了四个数据库,查找报告因 AECOPD 住院患者的抑郁症筛查或治疗情况的出版物。文章的识别基于系统评价和荟萃分析的首选报告项目 (PRISMA) 声明。在筛选的 1494 篇原创文章中,有 35 篇符合所有纳入标准。这些报告显示 AECOPD 中抑郁症的患病率在 9.5% 到 85.6% 之间。一些研究报告抑郁性 AECOPD 患者的入院后死亡率较高,并且与非抑郁性 AECOPD 患者相比,抑郁性 AECOPD 患者的再入院率较高。重要的是,这 35 篇出版物中没有一篇包含有关 AECOPD 抑郁症筛查和管理的建议。抑郁症和 AECOPD 经常同时发生,这会使结果恶化。然而我们没有找到管理方面的建议,也很少有干预研究。应对因 AECOPD 住院的患者进行系统的抑郁症筛查,并为这些患者制定治疗建议。有必要对住院 AECOPD 患者如何筛查和治疗抑郁症进行随机研究。因 AECOPD 住院的患者应接受抑郁症筛查并制定治疗建议 http://ow.ly/p1g430bspOA
Patients with acute exacerbated chronic obstructive pulmonary disease (AECOPD) and concurrent depression suffer significant psychological stress and decreased quality of life. The aim of this study was to collate data, guidelines and recommendations from publications on the screening and management of depressive mood disorders in patients hospitalised with AECOPD. We systematically searched four databases for publications reporting screening or management of depression in patients hospitalised for AECOPD. The identification of articles was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Out of 1494 original articles screened, 35 met all inclusion criteria. These report a prevalence of depression in AECOPD ranging between 9.5% and 85.6%. Some studies report high postadmission mortality rates for depressive AECOPD patients, and higher readmission rates in depressive versus nondepressive AECOPD patients. Importantly, none of the 35 publications included suggestions on the screening and management of depression in AECOPD. Depression and AECOPD frequently co-occur, and this worsens outcomes. Yet we did not find recommendations on management, and few interventional studies. Patients hospitalised with AECOPD should be systematically screened for depression and treatment recommendations should be developed for these patients. Randomised studies on how to screen and treat depression in hospitalised AECOPD are necessary. Patients hospitalised for AECOPD should be screened for depression and treatment recommendations should be developed http://ow.ly/p1g430bspOA
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