Electrophoretic Karyotypes of Candida Yeasts Recurrently Isolated from Single Patients

Electrophoretic Karyotypes of Candida Yeasts Recurrently Isolated from Single Patients
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从单个患者中反复分离的念珠菌酵母的电​​泳核型

DOI:
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发表时间:
1994
影响因子:
2.6
通讯作者:
Kenji Tanaka
Kenji Tanaka
中科院分区:
医学4区
文献类型:
--
作者:
Matsuko Doi;I. Mizuguchi;M. Homma;Kenji Tanaka

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在医院念珠菌感染复发期间,从单个患者中反复分离念珠菌菌株,并使用CHEF系统通过脉冲场凝胶电泳分析其电泳核型。当只有C.白色念珠菌(6例);光滑酵母菌(1例)反复分离,核型基本一致,提示携带单一型酵母菌。当从单个患者(6例)中回收多个菌种时,最常回收的酵母菌种的核型几乎与每个患者相同。电泳核型分析不仅可以进行种属鉴定,而且可以区分同一种属的不同菌株,在流行病学研究中具有重要的应用价值。
Candida strains were isolated repeatedly from single patients during recurrent episodes of Candida infection in a hospital, and their electrophoretic karyotypes were analyzed by pulsed‐field gel electrophoresis using CHEF system. When only C. albicans (in 6 patients) or C. glabrata (in 1 patient) were recurrently isolated, their karyotypes from each patient were almost identical to one another, suggesting that they carried single type of the yeast. When multiple species were recovered from single patients (6 cases), the karyotypes of the most frequently recovered yeast species were almost identical with respect to each patient. The electrophoretic karyotype analysis has been proved to be useful for epidemiological studies because the method can tell not only the species identification but also the differences among the strains of the same species.
酿酒酵母遗传图谱,第 9 版。
DOI: 10.1128/mr.49.3.181-213.1985
发表时间: 1985
期刊: Microbiological reviews
影响因子: --
作者:
Mortimer,RK;Schild,D
通讯作者: Schild,D