Mortality Predictors in ST-Elevated Myocardial Infarction Patients Undergoing Coronary Artery Bypass Grafting

Mortality Predictors in ST-Elevated Myocardial Infarction Patients Undergoing Coronary Artery Bypass Grafting
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接受冠状动脉搭桥术的 ST 段抬高型心肌梗死患者的死亡率预测因子

DOI:
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发表时间:
2011
期刊:
影响因子:
2.8
通讯作者:
I. Yekeler
I. Yekeler
中科院分区:
医学3区
文献类型:
--
作者:
U. Filizcan;E. Kurç;S. Cetemen;O. Soylu;H. Aydoǧan;Olgar Bayserke;M. Yilmaz;H. Uyarel;M. Ergelen;G. Orhan;M. Uğurlucan;E. Eren;I. Yekeler

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冠状动脉旁路移植术(CABG)在急性心肌梗死的初级治疗中的应用仍有争议。我们评估了ST段抬高型心肌梗死(STEMI)患者接受直接CABG的死亡率预测因素。在2003年1月至2008年1月期间,所有转诊至我们机构的STEMI患者均不符合直接血管成形术的条件,需要CABG。回顾性比较了存活者和非存活者的人口统计学、术前、术中和术后特征。分析中纳入了术前确诊的STEMI病例(n = 150)。有114人幸存,36人死亡。住院死亡率为22%。在考克斯回归分析中,年龄、心源性休克(Killip ≥3)、术前心肌肌钙蛋白水平、术前使用主动脉内球囊反搏(IABP)、既往心肌梗死和经皮冠状动脉介入治疗是院内死亡率的独立预测因素。经多因素分析,预测住院死亡率的因素是年龄、术前心肌肌钙蛋白水平和术前IABP。年龄、术前心肌肌钙蛋白水平和术前IABP使用是因STEMI行直接CABG患者院内死亡率的预测因素。
The use of coronary artery bypass grafting (CABG) in primary treatment of acute myocardial infarction is still debated. We evaluated the predictors of mortality in patients undergoing primary CABG for ST-elevated myocardial infarction (STEMI). Between January 2003 and January 2008, all patients referred to our institution with STEMI who did not qualify for primary angioplasty and required CABG were included in this study. Survivors and nonsurvivors were compared retrospectively in terms of demo-graphics, preoperative, intraoperative, and postoperative characteristics. Preoperatively confirmed cases of STEMI (n = 150) were included in the analysis. There were 114 survivors and 36 nonsurvivors. In-hospital mortality rate was 22%. In Cox regression analysis age, cardiogenic shock (Killip ≥3), preoperative cardiac troponin levels, preoperative use of intra-aortic balloon counterpulsation (IABP), previous myocardial infarction, and percutaneous coronary intervention were independent predictors of in-hospital mortality. After multivariate analysis, factors predicting in-hospital mortality were age, preoperative cardiac troponin levels, and preoperative IABP. Age, preoperative cardiac troponin levels, and preoperative IABP use were predictive factors of in-hospital mortality in patients undergoing primary CABG for STEMI.
DOI: 10.1056/nejm199610313351802
发表时间: 1996-10-31
影响因子: 158.5
作者:
Antman, EM;Tanasijevic, MJ;Braunwald, E
通讯作者: Braunwald, E