Differences in muscle satellite cell dynamics during muscle hypertrophy and regeneration.
Differences in muscle satellite cell dynamics during muscle hypertrophy and regeneration.
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DOI：
10.1186/s13395-022-00300-0
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发表时间：
2022-07-06
期刊：
影响因子：
4.9
通讯作者：
中科院分区：
文献类型：
--
作者：
骨骼肌的稳态和功能是由几种类型的细胞之间协调的细胞相互作用来确保的。骨骼肌生物学的一个值得注意的方面是在多种情况下发生的细胞间通讯的剧烈变化。从损伤中恢复的过程被称为再生，已经得到了相对较好的研究。然而，与再生相比，对机械负荷（例如在阻力训练期间）的反应中发生的细胞相互作用知之甚少。在肌肉再生期间，肌肉卫星细胞（MuSC）通过增殖、分化、融合和成熟的逐步过程重建多核肌纤维，而在机械负荷依赖性肌肉肥大期间，MuSC不经历这样的逐步过程（除了在罕见的损伤中），因为MuSC的核直接并入成熟的肌细胞核中。在这篇综述中，六个具体的例子，这样的差异，在MuSC的动态再生和肥大过程进行了讨论。
Skeletal muscle homeostasis and function are ensured by orchestrated cellular interactions among several types of cells. A noticeable aspect of skeletal muscle biology is the drastic cell–cell communication changes that occur in multiple scenarios. The process of recovering from an injury, which is known as regeneration, has been relatively well investigated. However, the cellular interplay that occurs in response to mechanical loading, such as during resistance training, is poorly understood compared to regeneration. During muscle regeneration, muscle satellite cells (MuSCs) rebuild multinuclear myofibers through a stepwise process of proliferation, differentiation, fusion, and maturation, whereas during mechanical loading-dependent muscle hypertrophy, MuSCs do not undergo such stepwise processes (except in rare injuries) because the nuclei of MuSCs become directly incorporated into the mature myonuclei. In this review, six specific examples of such differences in MuSC dynamics between regeneration and hypertrophy processes are discussed.
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影响因子：
16.6
作者：
Hansson KA;Eftestøl E;Bruusgaard JC;Juvkam I;Cramer AW;Malthe-Sørenssen A;Millay DP;Gundersen K
通讯作者：
Gundersen K
影响因子：
16.6
作者：
Cramer AAW;Prasad V;Eftestøl E;Song T;Hansson KA;Dugdale HF;Sadayappan S;Ochala J;Gundersen K;Millay DP
通讯作者：
Millay DP
DOI：
10.1038/nrm3591
发表时间：
2013-06
期刊：
Nature reviews. Molecular cell biology
影响因子：
--
作者：
通讯作者：
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影响因子：
11.4
作者：
Girgenrath, Mahasweta;Weng, Shawn;Zheng, Timothy S.
通讯作者：
Zheng, Timothy S.
影响因子：
21.3
作者：
Joe AW;Yi L;Natarajan A;Le Grand F;So L;Wang J;Rudnicki MA;Rossi FM
通讯作者：
Rossi FM