Stem cells and the niche: a dynamic duo.

Stem cells and the niche: a dynamic duo.
复制标题

DOI:
10.1016/j.stem.2010.01.011
复制
发表时间:
2010-02-05
期刊:
影响因子:
23.9
通讯作者:
Jones DL
Jones DL
中科院分区:
医学1区
文献类型:
--
作者:
Voog J;Jones DL

文献摘要

参考文献

被引文献

相似文献

干细胞生态位是平衡干细胞活性以维持组织稳态和修复的动态微环境。监测和干扰生态位组分的策略的发展提供了对生态位的响应性质的洞察,并提供了一个框架来揭示正常干细胞生态位功能的破坏如何有助于衰老和疾病的发生和进展。在鉴定调节干细胞小生境的形成、活性和大小的遗传因子方面的额外工作将有助于将小生境纳入基于干细胞的治疗和再生医学。
Stem cell niches are dynamic microenvironments that balance stem cell activity to maintain tissue homeostasis and repair throughout the lifetime of an organism. The development of strategies to monitor and perturb niche components has provided insight into the responsive nature of the niche and offers a framework to uncover how disruption of normal stem cell niche function may contribute to aging and disease onset and progression. Additional work in the identification of genetic factors that regulate the formation, activity, and size of stem cell niches will facilitate incorporation of the niche into stem cell-based therapies and regenerative medicine.
DOI: 10.1016/s1534-5807(02)00254-x
发表时间: 2002-09-01
期刊: DEVELOPMENTAL CELL
影响因子: 11.8
作者:
Conboy, IM;Rando, TA
通讯作者: Rando, TA
DOI: 10.1038/nature03260
发表时间: 2005-02-17
期刊: NATURE
影响因子: 64.8
作者:
Conboy, IM;Conboy, MJ;Rando, TA
通讯作者: Rando, TA
DOI: 10.1111/j.1365-2184.1971.tb01536.x
发表时间: 1971-01-01
期刊: CELL AND TISSUE KINETICS
影响因子: --
作者:
AMSEL, S;DELL, ES
通讯作者: DELL, ES
DOI: 10.1016/j.ydbio.2009.10.045
发表时间: 2010-02-01
影响因子: 2.7
作者:
Beebe, Katherine;Lee, Wen-Chih;Micchelli, Craig A.
通讯作者: Micchelli, Craig A.
DOI: 10.1126/science.1144090
发表时间: 2007-08-10
期刊: SCIENCE
影响因子: 56.9
作者:
Brack, Andrew S.;Conboy, Michael J.;Rando, Thomas A.
通讯作者: Rando, Thomas A.