Validity of Clinical Body Weight Measures as Substitutes for Missing Data in a Randomized Trial.
Validity of Clinical Body Weight Measures as Substitutes for Missing Data in a Randomized Trial.
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DOI：
10.1016/j.orcp.2008.09.002
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发表时间：
2008-12
影响因子：
4.3
通讯作者：
Simon, Greg E.
中科院分区：
文献类型：
--
作者：
Arterburn, David;Ichikawa, Laura;Ludman, Evette J.;Operskalski, Belinda;Linde, Jennifer A.;Anderson, Emily;Rohde, Paul;Jeffery, Robert W.;Simon, Greg E.
减肥干预措施的长期随访是必不可少的，但收集体重可能很困难，自我报告也不准确。我们研究了在减肥试验和常规临床护理中获得的体重测量值之间的关系。对88名肥胖妇女和203名年龄在40至65岁之间的肥胖和抑郁共病妇女进行了行为肥胖治疗试验，并将体重数据与常规临床护理期间输入电子病历（EMR）的体重数据进行了比较。然后使用散点图、Pearson相关性和t检验比较6个月和12个月时的研究和EMR重量和重量变化。该试验的12个月随访率为77%。在224名12个月的完成者中，142名妇女（63%）在12个月研究体重的90天内有EMR体重。研究和EMR体重高度相关（0.99），平均差异为0.1 kg。使用研究和EMR权重的12个月体重变化的两个测量值之间的相关性为0.96。这些结果对敏感性分析具有稳健性，该分析探索了不同大小的窗口对临床权重与研究权重匹配的影响。在12个月时缺失研究体重的67名女性中，33名（49%）在错过随访预约的90天内获得了EMR体重。在临床护理中常规获得的体重测量值与经过培训的研究人员获得的体重测量值高度相关，并且可以在不进行统计学校正的情况下用于在体重减轻研究中实现更高的长期随访率。
Long-term follow-up of weight loss interventions is essential, but collecting weights can be difficult, and self-reports inaccurate. We examined the relationship between weight measures obtained in the context of a weight loss trial and in routine clinical care. Body weight data from a trial of behavioral obesity treatment among 88 obese women and 203 women age 40 to 65 years with comorbid obesity and depression were compared against weight data entered into an electronic medical record (EMR) during routine clinical care. Study and EMR weights and weight changes were then compared at 6 and 12 months using scatterplots, Pearson’s correlations, and t-tests. The 12-month follow-up rate for this trial was 77%. Among the 224 12-month completers, 142 women (63%) had an EMR weight within 90 days of their 12-month study weight. Study and EMR weights were highly correlated (0.99), with a mean difference of 0.1 kg. The correlation between two measures of 12-month weight change using study and EMR weights was 0.96. These results were robust to sensitivity analyses that explored the impact of different-sized windows for matching clinical weights with study weights. Among the 67 women who were missing study weights at 12 months, 33 (49%) had an EMR weight available within 90 days of their missed follow-up appointment. Weight measures routinely obtained in clinical care are highly correlated with those obtained by trained research staff and may be used, without statistical correction, to achieve higher rates of long-term follow-up in weight loss studies.
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影响因子：
4.4
作者：
STEVENS, VJ;WAGNER, EL;GREENLICK, MR
通讯作者：
GREENLICK, MR
DOI：
10.1046/j.1467-789x.2003.00109.x
发表时间：
2003-08-01
期刊：
Obesity reviews : an official journal of the International Association for the Study of Obesity
影响因子：
--
作者：
Gadbury, G L;Coffey, C S;Allison, D B
通讯作者：
Allison, D B
影响因子：
5.1
作者：
Linde, Jennifer A.;Jeffery, Robert W.;Rohde, Paul
通讯作者：
Rohde, Paul
DOI：
10.1016/s0002-8223(01)00008-6
发表时间：
2001-01-01
影响因子：
--
作者：
Kuczmarski, MF;Kuczmarski, RJ;Najjar, M
通讯作者：
Najjar, M
影响因子：
2.5
作者：
DiMaria-Ghalili, Rose Ann
通讯作者：
DiMaria-Ghalili, Rose Ann